Skin Cancer Flashcards
1
Q
UV-A effects
A
Produces reactive oxygen species causing oxidative DNA and protein damage
Skin ageing
Potentates UV-B carcinogenesis
2
Q
UV-B effects
A
Sunburn
Direct damage of skin cell DNA
3
Q
Most common skin cancers
A
- BCC
- SCC
- Malignant melanoma
4
Q
Which skin conditions require a 2ww referral
A
MM
SCC
5
Q
A-E examination of melanoma
A
A: asymmetrical
B: irregular border
C: irregular pigmentation
D: >6mm diameter
E: evolution - change in size, colour and elevation
Oozing, bleeding, itching, altered sensation
6
Q
Premalignant skin conditions
A
Actinic keratosis
Bowens disease
7
Q
Character of BCC
A
Rarely metastasises
8
Q
Character of SCC
A
Can metastasise
9
Q
When should BCCs be referred to haematology
A
Head and neck lesions
10
Q
Surgical margins for each skin cancer
A
BCC: 3-5mm SCC: 2-4mm Melanoma in situ: 5mm Melanoma <2mm deep: 1cm Melanoma >2mm deep: 2cm
11
Q
Treatment options for skin cancers
A
Sunscreen Retinoids 5-FU Photodynamic therapy Cryotherapy Surgical excision
