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Core Clinical Problems > Immunology > Flashcards

Immunology Flashcards

1
Q

Addison’s Disease

A

Anti-21-hydroxylase

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2
Q

Anti-phospholipid Syndrome

A

Anti-cardiolipin

Lupus anticoagulant antibodies

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3
Q

Autoimmune Haemolytic Anaemia

A

Red blood cell antibodies

Warm or Cold - temp antibodies best attach to red cell

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4
Q

Autoimmune Hepatitis

A

Anti-Nuclear
Anti-smooth muscle
Anti-liver/kidney microsomal-l
pANCA (myeloperoxidase anti-nuclear cytoplasmic antibody (MPO-ANCA)

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5
Q

Churg-Strauss syndrome

A

MPO-ANCA

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6
Q

Coeliac Disease

A

Anti-endomysial
Anti-tissue transglutaminase
Anti-gliadin
Anti-reticulum

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7
Q

Scleroderma

A

Rheumatoid factor
ANA

Diffuse: anti-ScL-70, polymerase 1 2 + 3

Limited: anti-centromere

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8
Q

Goodpasture Syndrome

A

Anti-glomerular basement membrane

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9
Q

Graves’ Disease

A

Anti-TSH receptor

Anti-peroxidase

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10
Q

Lambert-Eaton Myasthenic Syndrome

A

Anti-P/Q-type voltage-gated calcium channels

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11
Q

Myasthenia Gravis

A

Anti-nuclear
Anti-acetylcholine receptor antibodies
Anti-MUSK (muscle specific tyrosine kinase)

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12
Q

Pernicious Anaemia

A

Anti-parietal cell

Anti-intrinsic factor

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13
Q

Polyarteritis Nodosa

A

MPO-ANCA

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14
Q

Polymyositis/dermatomyositis

A

Anti-Jo-1
ANA
Rh.F

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15
Q

Primary Biliary Cirrhosis

A

Anti-mitochondrial

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16
Q

Rheumatoid Disease

A

Rheumatoid factor
Anti-nuclear
Anti-CCP

17
Q

Sjören Syndrome

A

Rh.F
ANA
Anti-Ro
Anti-La

18
Q

SLE

A

Anti-dsDNA (double stranded)
Rh.F
ANA
Anti-cardiolipin

19
Q

Granulomatosis with polyangitis

A

cANCA

PR3-ANCA

Core Clinical Problems (10 decks)

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