Telomerase ​ Flashcards

1
Q

Telomerase - O que é? / Tipo de Enzima 2

A

Enzima descoberta em 1985

Enzima Ribonucleoproteica

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2
Q

Telomerase - Quantidade

A

Nascemos com muita → mas diminui drasticamente após a infância

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3
Q

Telomerase - Função

A

Aumenta os telômeros → ao adicionar sequências específicas e repetitivas de DNA à extremidade 3’ dos telômeros.

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4
Q

Telomerase - Mecanismo de Ação

A

Atividade de Transcriptase Reversa (TR) → faz DNA telomérico à partir de RNA

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5
Q

Telomerase - Origem

A

Gene TERT

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6
Q

Telomerase - ↓ Telomerase

A

Vida Reprodutiva Curta

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7
Q

Telomerase - ↑ Telomerase

A

Vida útil maior → e um envelhecimento mais lento

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