Lecture 21: gluconeogenesis Flashcards
1
Q
Where does gluconeogenesis occur?
A
the liver and kidney
2
Q
What are the major precursors of gluconeogenesis?
A
lactate, amino acids, glycerol
3
Q
Where is glucose 6 phosphate located?
A
lumen of the endoplasmic reticulum
4
Q
What does the T1 protein do?
A
transports glucose 6 phosphate to ER
5
Q
what does the T2 protein do?
A
transports inorganic phosphate back into cytosol
6
Q
What does the T3 protein do>?
A
transports glucose back into the cytoplasm
7
Q
How are glycolysis and gluconeogenesis regulated in the liver?
A
fructose 2,6 bisphospahte strongly stimulates phosphofructokinase and inhibits fructose 1,6 bisphosphate
8
Q
What enzymes regulate the concentration of fructose 2,6 bisphosphate?
A
phosphofructosekinase 2 and fructose bisphophatase 2
