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Renal > Urinary Tumours > Flashcards

Urinary Tumours Flashcards

1
Q

most common bladder tumour type?

A

transitional cell carcinoma

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2
Q

squamous cell carcinoma occurrence?

A

where schistosomiasis is endemic

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3
Q

bladder cancer risk factors?

A

smoking
aromatic amines
genetics

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4
Q

SCC risks?

A

schistosomiasis
chronic cystitis
cyclophosphamide therapy

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5
Q

more frequent presentation in bladder cancer?

A

painless visible frank haematuria
recurrent UTI
storage problems

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6
Q

investigations of haematuria?

A 
urine culture
cystourethroscopy
CT urogram
BP
U&Es
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7
Q

diagnosis in bladder cancer?

A

cystoscopy and endoscopic resection (TURBT)

EUA to assess bladder mass/thickening

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8
Q

what is CIS?

A

carcinoma in situ

non-muscle invasive but VERY aggressive

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9
Q

treatment in low grade bladder cancer?

A

endoscopic resection followed by single instillation of intravesical chemo 24hrs

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10
Q

treatment in high grade or CIS bladder cancer?

A

endoscopic resection

intravesical BCG therapy (weekly 3 weeks, 6 monthly)

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11
Q

treatment in muscle invasive?

A

neodjuvant chemotherapy followed by radiotherapy with or without radical cystoprostatectomy

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12
Q

Upper tract TCC symptoms?

A

frank haematuria
unilateral ureteric obstruction
flank/loin pain

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13
Q

Upper tract TCC investigations?

A

CT-IVU

shows filling defects in the renal pelvis

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14
Q

risks in renal cancer?

A

antihypertensives
FH
obesity
smoking

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15
Q

benign renal cancers?

A

oncocytoma

angiomyolipoma

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16
Q

malignant renal cancer?

A

renal adenocarcinoma

17
Q

where do most renal adenocarcinoma arise from?

A

proximal tubules

clear cell, papillary, chromophore

18
Q

renal cancer presentation?

A

asymptomatic in 50%
triad: flank pain, mass, haematuria
paraneoplastic syndrome

19
Q

renal cancer investigations?

A

CT scan of abdomen and chest
bloods - U&E and FBC
US - cyst?

20
Q

treatment in renal cancer?

A

radical nephrectomy

21
Q

key concern in renal cancer metastases?

A

RCC is radio resistant and chemoresistant

Renal (11 decks)

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