Raised ICP Flashcards

1
Q

What are normal ranges of ICP in adults children and infants ?
what is a good rule of thumb for raised ICP ?

A

Adults= 5-15 mmHg
Children = 5-7mmHg
Term infants = 1.5 - 6 mmHg

if >20mmHg = raised

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2
Q

what is the Monro-kellie doctrine ?

A

Any increase in the volume of one of the intracranial

constituents (brain, blood or CSF) must be compensated by a decrease in the volume of the one of the others

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3
Q

what is the first components to decrease in IC mass ?

A

CSF and venous blood, since they are at the

lowest pressure

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4
Q

how do you work out CPP?

What is normal CCP , MAP and ICP

A

CPP = mean arterial pressure (MAP) – ICP
CPP >70 MMhG
MAP ~90mmHg
ICP ~10 mmHg

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5
Q

What happpens when CPP is <50 mmHg ?

A

cerebral blood flow cannot be

maintained as cerebral arterioles are maximally dilated

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6
Q

what can damage brain lead to ?

A

impair or even abolish cerebral

auto-regulation (Vaso contriction/ dilation)

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7
Q

what happens in Cushing triad/ reflex ?

A

Raised ICP -
Hypertension = Increase in MAP to maintain CPP
Bradycardia = Due to vagal activity via baroreceptors from increased MAP
Irregular breathing = compression of the brainstem leads to
damage to respiratory centres

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8
Q

what mights cause raised ICP from blood ?

A

too much in vessels -
Raised arterial pressure = Malignant hyperntsion
Raised venous = SVC obstruction
Haemorrhage- SA, SD, ED, Stroke and intraventricular

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9
Q

what are the cause of Hydrocephalus ?

A

too much CSF

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10
Q

What are the causes of congenital hydrocephalus ?

A

Obstructive - Neural tube defects, Aqueduct stenosis, part of other syndromes
Communicating- Increased CSF production , Decreased CSF absorption

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11
Q

what are the clinical signs of congenital hydrocephalus ?

A
Bulging head with head
circumference increasing faster than
expected
Sunsetting eyes (due to direct
compression of orbits as well as
involvement of oculomotor nerve as it
exits midbrain)
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12
Q

what is the management of congenital hydrocephalus ?

A

tapping fontanelle with needle
Medium term drainage can be achieved by external ventricular drain
(EVD)

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13
Q

what is the advantages / disadvantages of EVD?

A

allows - Short / medium term drainage , continuous pressure monitoring , used if shunt fails or contraindicated
cons - Infection pathway , chamber must be kept at same height as ventricles
inpatient monitoring - not long term

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14
Q

what is a Ventricular shunt ? what types can you get ?

A

one way valve tunelled under skin
tube is placed from the ventricular system
into the peritoneum (V-P) or
right atrium (V-A), VP more common

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15
Q

what are cons of VP shunts ?

A
Extra length of tubing is
provided to allow growth
before revision is required
V-P shunts vulnerable to
infection (e.g. if abdominal
infection, can track back up to
brain) or kinking Most s
hunts will require
revision
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16
Q

what are some acquired forms of hydrocephalus ?

A
Meningitis
Trauma
Haemorrhage (e.g. post subarachnoid
haemorrhage)
 Tumours (e.g. compressing cerebral
aqueduct)
17
Q

What are the 4 types of cerebral oedema ?

A

Vasogenic -
Cytotoxic
Osmotic
Interstitial

18
Q

what are each types pathologies (Cerebral oedema )?

A

v - Breakdown of tight junctions at BB due to vasoactive substances
C- damage to brian cels ia toxins
O- ECF becomes hypotonic due to SIADH or excessive H20 intake
I - Flow of CSF to due to rupture of BB from hydrocephalus trauma

19
Q

what are alternative Causes of raised ICP?

A

Tumour
Cerebral abscess
Idiopathic

20
Q

what is IIH ?
Symptoms ?
associations ?

A

Idiopathic intracranial hypertension - Aka benign intracranial hypertension
headache and visual
disturbance
Usually obese middle aged females

21
Q

how is IIH diagnosed ?
what must you be careful of ?
management ?

A
raised
opening pressure on an LP
no signs of
intracranial pathology before doing an LP in a patient with suspected raised ICP as this can
precipitate brain herniation

weight loss and BP control

22
Q

what are early symptoms of Raised ICP ?

A
Headache 
nausea and vomiting 
Difficulty concentrating or drowsiness - Daily life
Confusion 
Double vision 
Focal nero signs
Seizures - blackouts
23
Q

what kind of headaches will a patient get in raised ICP ?

A

Constant
o Worse in the morning
o Worse on bending / straining

24
Q

what specially will be wrong with vision ?

A
Problems with accommodation (early sign,
pupillary dilatation a late sign)
o Maybe effects on acuity
o Visual field defects
o Papilloedema
25
Q

define tonsillar herination

A

Cerebellar tonsils herniate through foramen

magnum, compressing medulla

26
Q

define subfalcine herination

A

Cingulate gyrus is pushed under the free edge of
the falx cerebri
Can compress anterior cerebral artery as it loops
over the corpus callosum

27
Q

define uncal herination

symptoms ?

A

Uncus of temporal lobe herniates through tentorial
notch compressing adjacent midbrain
Can cause third nerve palsy and maybe even
contralateral hemiparesis (due to compression of
cerebral peduncle)

28
Q

define central downward herniation

A

Medial temporal lobe / other midline structures

pushed down through tentorial notch

29
Q

define external herniation

A

skull fracture or therapeutic

craniectomy

30
Q

what are brain protective measures ?

A
airway and breathing control 
Circulation 
sedation, analgesia and paralysis 
Head up tilt - improve drainage 
Temperature - avoid high temps
Anticonvuslants
Nutritions and PPIs - increased Vagal activity
31
Q

what are treatment options ?

A

Mannitol or hypertonic saline
o Osmotic diuresis
• Ventricular drainage
• Decompressive craniectomy as a last resort