Pancreas

Question 1

What type of cells are found in pancreas?

Answer 1

Exocrine cells

Islet of Langerhans = alpha, eta and delta

Question 2

What are the endocrine cells of the pancreas?

Answer 2

Islet of Langerhans - alpha, beta, delta

Question 3

What do alpha cells secrete?

Answer 3

Glucagon

Question 4

What do beta cells secrete?

Answer 4

Insulin

Question 5

What do defat cells secrete?

Answer 5

Somatostatin

Question 6

What is the effect glucagon on glucose?

Answer 6

Increase

Question 7

What is the effect of insulin on glucose?

Answer 7

Decrease

Question 8

What is the effect of somatostatin?

Answer 8

Regulates insulin dn glucagon secretion (inhibits)

Question 9

All 3 hormones released from pancreas are peptide hormones. How are they released from secreting cell?

Answer 9

Exocytosis

Question 10

What pathway does insulin activate in target cells?

Answer 10

Tyrosine kinase pathway

Question 11

What pathways do glucagon and somatostatin activate in target cells?

Answer 11

cAMP signal transduction pathway

Question 12

What stimulates the release of insulin?

Answer 12

Raise blood glucose, increased AA and digestive hormones

Question 13

Why does increased AA increase insulin release?

Answer 13

Used to promote protein synthesis

Question 14

What decreases insulin release?

Answer 14

Low blood glucose, somatostatin

Question 15

What is DM classified by?

Answer 15

Elevated blood glucose

Question 16

Why does DM cause thirst?

Answer 16

Glucose is osmotically active ad causes blood osmolarity to increase, lots of water taken up to bing osmolarity back down again

Question 17

What is the difference between type 1 and type 2 diabetes?

Answer 17

Type 1 = beta cell destruction

type 2 = don’t respond to insulin