classical conditioning- lecture 1 Flashcards

1
Q

what is long term potentiation

A

where synapses become more powerful

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2
Q

what is the unconditioned stimulus

A
food 
electric shock (periorbital shock)
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3
Q

what is the unconditioned response

A

salivation

nictitating membrane

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4
Q

what is the conditioned stimulus

A

bell

noise

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5
Q

conditioned response

A

salivation
movement of the nictitating membrane.
typically similar to the UR.

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6
Q

why study eyeblink conditioning

A

simple response easy to study, nictitating membrane has no voluntary control, but can be classically conditioned.

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7
Q

100 trials a day of nictitating eye blink

A

day 1: response to US only
Day 3- evidence of eyelid movement before US arrives
day 5- cr clear to see the eyelid closes in anticipation of the US

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8
Q

what is delay conditioning

A

the US comes on before the CS stops and overlaps.

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9
Q

what is trace conditioning

A

gap between the auditory stimulus and US- more complex than delay conditioning

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10
Q

definition of classical conditioning

A

the CR does not affect the CS. otherwise it would be a form of avoidance learning.

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11
Q

where was the first place researchers looked and why

A

The hippocampus

patient HM.

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12
Q

Does damage to the hippocampus stop eyeblink conditioning

A

NO=
Weiskrantz and Warrington (1979) examined patients with anterograde amnesia- clear evidence of learning - no conscious awareness.

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13
Q

types of long term memory

A

conscious memory: declarative.

semantic, episodic, and procedural.

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14
Q

Thompson (1983)- cerebral cortex and hippocampus

A

delay NMR conditioning still possible in rabbits lacking either hippocampus or cerebral cortex. also possible in decerebrate animals. (separated).
This led them to research the cerebellum.

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15
Q

Electrophysiological recording of the cerebellum

A

McCormick and Thompson (1984)- when paired the units in the brain increase responding.

  • recording from the deep cerebellar nuclei
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16
Q

problem with recordings

A

does not establish a causal role.

17
Q

Lesion studies

A

Large lesions of the entire cerebellum plus output nuclei- CR abolished and cannot be relearnt.
Similar effect when lesions are refined to the deep cerebellar nuclei.

Yeo et al., (1985) refined to small lesions of the anterior interpositus nucleus also abolished conditioning.

18
Q

behavioural effects of lesions

A

loss of CR. UCR not affected.
important in showing that the lesion does not produce a simple motor deficit.

unilateral lesions account for deafness - conditioning still possible in other eye.

19
Q

also evidence in people

A

Ramnani et al (2000) imaging.

Gerwig et al (2003) cerebellar atrophy.