WEEK 4: CARBOHYDRATES: DIGESTIBLE AND INDIGESTIBLE Flashcards

1
Q

Carbohydrates Classification

A
Monosaccharides
– simplest carbohydrates 
– C6H12O6 (glucose) 
Disaccharides 
– 2 monosaccharides bound 
– C12 H22O11 (maltose) 
Polysaccharides 
– many monosaccharides bound 
– complex carbohydrates: glycogen, starch, fibre 
– (C6 H12 O6)n
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Monosaccharide

A
6 CARBON SINGLE UNITS:
– Glucose 
– Fructose 
– Galactose 
– Sugar alcohols: xylitol, mannitol and sorbitol (= low calorie sweeteners) 
5 CARBON SINGLE UNITS: 
- Ribose 
- Deoxyribose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Glucose

A
  • A hexose, C6H12O6
  • Most abundant monosaccharide
  • Consumed as sucrose
    (glucose + fructose)
  • Constitutes “blood sugar level”
  • GLUT4 is insulin dependent
  • Undergoes glycolysis or glycogenesis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Fructose

A
  • Varies from glucose in that the carbonyl group is on C-2 rather then C-1
  • Is the sweetest monosaccharide
  • Found in fruit, honey, vegetables
  • Cell uptake is not insulin dependent
  • Thought to be a good sugar because blood sugar level only measures glucose… but it does get transformed to glucose inside the cell
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Galactose

A
  • Differs from glucose only in the orientation of the OH group around C-4
  • With glucose, forms lactose (milk sugar)
  • Also present in some vegetables
  • Is the least sweet of the
    monosaccharides
  • Converted to glucose in the liver
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Role of Carbohydrates

A
  • The basis of structural tissue in plants e..g cellulose
  • Source of energy and blood glucose homeostasis
  • Substrate in the biosynthesis of other compounds: e.g. fat, ribose in ribonucleic acid
  • Cell to cell recognition and communication: saccharides are used in the formation of glycoproteins that sit on the surface of cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Glycoprotein cell receptors

A
  • surface carbohydrates on cells serve as points of attachment for other cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Galactosemia

A
  • reduction in the metabolism of galactose to glucose due to deficient galactokinase or other metabolism genes
  • galactose build-up leads to bacterial infections, mental retardation and cataracts
  • management: switch to soy formula at infancy, throughout life avoid dairy product, organ meats and some fruit, nuts and vegetables containing galactose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Sugar Alcohols

A
  • derivatices of mono, di or polysaccharides
  • class of polyols, 1 OH group attached to each carbon
  • not fully absorbed in SI, femented by bacteria in LI - therefore used as low energy sweeteners
  • with large quantities may induce bloating, diarrhoea and flatulence as water is drawn into the colon and bacterial fermentation
  • occurs naturally in some fruit and vegetable but usually issues from hydrogenation of sugars (sorbitol, mannitol, xylitol) or via fermentation of sugars (erythritol)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pentose Monosaccharides

A
  • ribose and deoxyribose
  • contains 5 carbons
  • essential part of cells genetic material - RNA and DNA
  • body makes own sypply via pentose phosphate pathway
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pentose Monosaccharides

A
  • ribose and deoxyribose
  • contains 5 carbons
  • essential part of cells genetic material - RNA and DNA
  • body makes own sypply via pentose phosphate pathway
  • found in nuts, meat, dairy, veges and is part of riboflavin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Disaccharides

A
  • two monosaccarides linked together by a condensation reaction
  • alpha or beta glycosidic bonds
  • maltose, lactose, sucrose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Maltose

A
  • glucose to glucose with alpha 1,4 glycosidic bond
  • energy tor sprout growth
  • used in food production in cereals, candies and brewing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Lactose

A
  • galactose to glucose with beta 1,4 glycosidic bond

- milk sugar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sucrose

A
  • glucose to fructose with alpha 1,2 glycosidic bond

- table sugar, sugarcane, in fruit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Lactose Intolerance

A

The inability to digest lactose
- primary: shortage of enzyme lactase in adulthood because of lactose non-persistence, which is default program in humans post weaning
- secondary: in lactase persistence phenotypes (in certain ethnicities and population with dairy farming ancestry), LI is associated with damage of lactase producing cells
symptoms (occur 30mins-2hours after digesting) - nausea, cramps, distension, gas, diarrhoea

17
Q

Oligosaccharides

A
  • contains 3-10 saccharides
  • e.g. raffinose and starchyose (onions, legumes, cabbage, broccoli)
  • mainly indigestible, may cause discomfort
18
Q

Polysaccharides

A
  • contains >10 saccharides
  • includes starch, glycogen, cellulose
  • digestibility depends on alpha or beta glycosidic bonds
19
Q

Starch

A
  • digestible
  • storage form of carbohydrate in plant
  • amylose: continuous chain of glucose molecules linked by alpha-1,4 glycosidic bonds
  • amylopectin: branched chain of glucose molecules linked by alpha-1,4 and alpha-1,6 glycosidic bonds. More quickly digested as more sites available to enzymes activity