Palliative care Flashcards
Analgesia should be ‘done’ by what three things?
By the ladder, by the clock, by the mouth (if poss)
How many times stronger than morphine is oxycodone?
2x
How many times stronger than morphine is fentanyl?
3x
Which two opioids are suitable for end stage renal failure?
Fentanyl or bupranorphine
What does a co-codamol dose of 30/500 mean?
30mg codeine, 500mg paracetamol
Why might you give co-codamol on the analgesic ladder?
It keeps ‘step 1’ paracetamol going as well as step 2, but combined in a tablet
SEs morphine
Constipation
N+V
Drowsy/clouded consciousness
Dry mouth
Itching
Reduced perception of breathlessness
Symptoms opioid toxicity
delirium
vivid dreams
visual hallucinations
myoclonus
decreased resp rate
pinpoint pupils
Immediate release morphine takes how long to work and lasts for how long?
within 30mins
Lasts 2-4hrs
Examples of IR morphine?
Oramorph
Sevredol
Modified release morphine lasts for how long
12 (or 24) hours
Examples modified release morphie
MST
Zomorph
Morphgesic
If a patient is on co-codamol 30/500 two tablets QDS and you want to add some morphine for breakthrough pain how much morphine would you prescribe?
30 x 2 x 4 = 240mg
240mg codeine = 24mg morphine
1/6 daily dose for breakthrough so 24/6 = 4
Prescribe 5mg (no more than 6-8 doses in 24hr)
What is the breakthrough morphine dose compared to MR dose?
1/6 daily total
How do you increase someone who is on MR and IR morphine?
Increase the MR to the current total daily dose, including IR (but only 1/3-1/2 increase is safe).
MR given BD
Is oramorph prescribed in mg or ml?
mg because it comes in 10mg/5ml and 100mg/5ml
What specific signs are there that you should reverse the opioid?
RR <8 and not rousable- reverse with naloxone
The SC dose of morphine is ____ the oral dose
half
Four causes of nausea and vomiting?
Cerebral
Toxicity (mainly nausea)
GI (mainly vomiting)
Ear
Two cerebral causes of nausea?
SOL
Anxiety/perception
Rx for cerebral nausea
SOL- Dex or cyclizine
Anxiety/perception- benzo/SSRI
Rx for chemo nausea
Ondansetron
Graniestron
Rx for the rest of the toxicity causes of nausea
Haloperidol
Which antipsychotics help with nausea?
Levomepromazine and olanzapine (but typical so SEs)
Can you give metaclopromide and cyclizine?
No they counteract each other
What are the four types of laxative?
Bulking agent
Softener
Stimulant
Combination
Fybogel is what sort of laxative?
Bulking agent