fungi Flashcards
Grows on wheat and Barley during wet season. Produces ergot toxin(neurotoxin), causes Seizures, hallucination,tremors, death.
Claviceps purpura- Ergotism
Fungus found in soil of dry low rainfall areas.endemic in many areas of SW USA,Mexico,C&S America. Valley fever, common cause of pneumonia in endemic areas.
Coccidioides imitis
Fungi causing systemic infection, primarily of lungs and central nervous system. Devision Basidiomycota. Pathogenic yeast found in soil enriched with bird/bat dropping.
Cryptococcus neoformans. Cryptococcosis. Decision Basidiomycota
Fungal meningitis. Opportunistic pathogen. Pathogenic yeast found in soil enriched with bird/bat dropping.Risk to immune compromised subjects. Inhalation of spores begins infection.
Treatment: Amphotericin B and Flucytosine ( 6-10 weeks)
Cryptococcal meningitis . Decision Basidiomycota
Deuteromycota. Red raised lesions on and around the toes and soles of the feet. Webbing between the toes is heavily infected.
Athlete’s foot. Tinea pedis.
Tines capitis
Ringworm. In human can be acquired following contact with contaminated soil or animals.Deuteromycota
Tinea cruris
Jock itch. Human mycoses. Usually spreads from the feet. Deuteromycota
Histoplasmosis. Deuteromycota
Mycoses of the lower respiratory system. Cause: dimorphic ascomycetes fungus. Signs: dry, unproductive cough, shortness of breath,chest pain,fever,chills,headache and malaise. Incubation period: 10days. More common in children up to 15yrs exposed to soil. Treatment: Itraconazole, ketoconazole or Amphotericin B.
Blastomycosis dermatitidis
Found in soil with decomposing organic matter. Enter through breaks in skin. Symptoms: similar to flu, include fever,chills,cough, muscle aches,joint pain and chest pain. Fungus can spread (disseminate) to other parts of the body such as skin and bones.
Mucormycosis
Most commonly affects the sinuses or lungs. Symptoms: sinus infection include fever, headache and sinus pain. Lung infections with fungus can cause fever and cough. Skin infection can develop after fungus enters through a break in the skin caused by surgery,burns or trauma. Skin infection can look like a blisters or ulcers and the infected tissue may turn black. Other symptoms of skin infection include fever and tenderness, pain, heat,excessive redness or swelling around a wound.
Candidiasis
Nonvenereal diseases of the reproductive system
Candida albicans
Entry: Mucous membrane. Signs and symptoms: white curdlike discharge, burning, itching, painful intercourse. Incubation period: typically 7-10 days. Susceptibility: women on anti microbial drugs, immune compromised individual such as AIDS patients. May overgrow after a course of antibiotics. Treatment: Antifungal drugs: Clotrimazole, Miconazole,Nystatin, diflucan,Amphotericin B. Prevention: avoid moisture in the genital area, good personal hygiene, use of probiotics( lactobacillus in yogurt).
Mycoses of the lower respiratory system caused by Pneuocystis jiroveci
Pneumocystis pneumonia (PCP). Signs: difficulty breathing, anemia,hypoxia and fever. Infection occurs by inhalation of droplets containing the fungus. Common disease in AIDS patients. Treatment: Trimethoprim and Sulfamethoxazole.
Fungi divisions:
Zygomycota, Ascomycota, Basidiomycota, Deuteromycota
Fungi Reproduction
Asexual : transverse fission, budding, spore production
Sexual: zygosopres, ascospores, basidiospores ( union of compatible nuclei followed by formation of sexual spores.