Past papers Histopath Flashcards

1
Q

cancer develops in Barrett’s oesophagus

A

adenocarcinoma

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2
Q

mechanism GORD -> cancer

A

metaplasia

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3
Q

body of stomach in pernicious anaemia

A

atrophy

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4
Q

Hy pylori cancer

A

MALT (or lymphoma)

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5
Q

Coeliac cancer

A

Enteropathy-associated Tc lymphoma

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6
Q

Caribbean and Japanese

HTLV-1

A

Adult Tc leukaemia/lymphoma

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7
Q

cancer, mycosis fungoides

A

Cutaneous Tc lymphoma

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8
Q

commonest breast malignancy

A

invasive ductal carcinoma

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9
Q

non-specific breast cancer

A

invasive ductal carcinoma

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10
Q

E-cadherin cancer

A

invasive ductal carcinoma

E-cadherin -ve= invasive lobular carcinoma

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11
Q

cancer with high, intermediate and low grade

A

DCIS

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12
Q

fibro-epithelial tumour with abundant stromal elements

A

pyllodes tumour

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13
Q

UTI, acute costovertebral pain

pus and blood in urine

A

acut pyelonephritis

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14
Q

loin-groin pain, haematuria

pain at end of micturition

A

calculus

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15
Q

frank painless haematuria

A

renal cell carcinoma

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16
Q

2y/o palpable abdo mass

A

Wilm’s tumour

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17
Q

PMH - AF

fever, N+V, right flank pain

A

renal infarct

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18
Q

heroin renal problem

A

focal glomerulonephritis

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19
Q

60 y/o abdo pain to back, collapses

A

AAA

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20
Q

ex-smoker, HTN and MI, sudden chest pain, radiates to back

A

descending internal carotid thrombus

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21
Q

AF plus flank pain

A

renal infarct

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22
Q

MI 3 years ago

sample from pericardial layer, blood aspirated

A

ventricular rupture

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23
Q

portal HTN clinical finding

A

splenomegaly

24
Q

cancer asbestos

A

mesothelioma

25
Q

transitional cell cancer

A

bladder

26
Q

itchy skin features in

A

hepatitis

27
Q

common ovarian tumour

A

serous cystadenoma (columnar epithelium)

28
Q

ulcers on mouth after drug

A

Steven-Johnson syndrome

29
Q

vector transmits Trypanosoma brucei rhodesiense

A

Tsetse Fly

30
Q

Leishmaniasis (also known as Kala Azar) vector

A

Sandfly

31
Q

True positives divided by the total number who have the disease

A

Sensitivity

32
Q

Hepatitis that doesnt lead to chronic Hep

A

Hep A

33
Q

cancer is most likely in a person who is a non-smoker

A

adenocarcinoma

34
Q

mallory bodies

A

alcoholic hepatitis

35
Q

child nephrotic syndrome cause

A

minimal change disease

36
Q

cancer of 50 y/o midshaft femur fracture

A

chondrosarcoma
>40

(whereas Ewing/ osteosarcoma young adults)

37
Q

diarrhoea, wt loss, biopsy granulomata

A

Crohn’s

38
Q

middle age F, biopsy liver - loss bile ducts and granulomas

A

PBC

39
Q

ALL blood count

A

neutropenia

40
Q

indications for dialysis

A
AEIOU
A - intractible acidosis
E - electrolyte disturbance
I - intoxiant e.g. methanol
O - fluid overload
U - uraemia Sx (N, seizure, pericarditis, bleed)
41
Q

subtypes endometrial cancer

A

endometrioid (E2)- 80%

non-endometrioid (papillary,serous,clear cell)

42
Q

breast bloody discharge, benign change

A

ductal papilloma

43
Q

Cancer from Barret’s

A

Adenocarcinoma

44
Q

Mechanism of GORD -> cancer

A

metaplasia

45
Q

Body of stomach in pernicious anaemia

A

atrophic gastritis

46
Q

H. pylori cancer

A

Gastric MALT

47
Q

Coeliac disease cancer

A

Enteropathy-associated MALT

48
Q

E-cadherin +ve

A

ductal

IDC

49
Q

enzyme if low, leads to hyperuricemia/rise in blood uric acid

A

HPGRT

50
Q

enzyme rate limiting step in haem biosynthesis pathway

A

ALA synthase

51
Q

enzyme is raised in osteomalacia

A

Alkaline phosphatase

52
Q

enzyme is raised in mumps

A

Amylase-S

amylase-P high in pancreatitis

53
Q

raised biomarker in rhabdomyolysis

A

Creatinine kinase

54
Q

HGPRT Deficiency resulting in urate overproduction

self mutilating, choreiform movements, mentally limited and gout

A

Lesch Nyhan

55
Q

transitional cell cancer organ?

A

bladder

56
Q

bone cancer
onion skin appearance
young adult

A

Ewing sarcoma

57
Q

bone cancer
sunburst appearance X ray
young adult

A

osteosarcoma (commonest primary bone ca)