8/20/13

Question 1

Type of immunity that recognizes molecules common to many pathogens

Answer 1

Innate Immunity

Question 2

Type of immunity that recognizes very specific macromolecules

Answer 2

Adaptive Immunity

Question 3

An antigen that can induce an immune response

Answer 3

Immunogen

Question 4

An antigen that cannot induce an immune response

Answer 4

Hapten (unless coupled with immunogen)

Question 5

Present peptide antigens to T-cells, determine tissue type for organ transplantation

Answer 5

MHC

Question 6

All leukocytes differentiate from this

Answer 6

hematopoetic stem cells in the bone marrow

Question 7

Immunity is conferred on individual when they are themselves infected or vaccinated

Answer 7

Active immunity

Question 8

If effectors are transferred from one individual to another, they confer_____

Answer 8

Passive Immunity

Question 9

Granulocytes/Polymorphonuclear cells

Answer 9

Neutrophils, Eosinophils, Basophils

Question 10

Short-lived Leukocyte, innate

Answer 10

Granulocytes (monocytes in b/w)

Question 11

Long-lived Leukocyte, adaptive

Answer 11

Lymphocytes, NK cells are innate (monocytes in b/w)

Question 12

Granulocytes recognize ____ targets by the presence of ______ and particles coated by _____. Granulocytes have an _____ ability to recognize a foreign invader

Answer 12

multiple, PAMPS, antibodies

Question 13

Lymphocytes recognize ____ target shape and a _____ fraction will be activated by a particular pathogen or invader

Answer 13

one, small

Question 14

Play a major role in late phase of hypersensitivity reactions

Answer 14

Eosinophils

Question 15

Play a major role in the immediate phase of hypersensitivity reaction

Answer 15

Basophils

Question 16

Antigen presenting cells that bridge the innate and adaptive immune systems

Answer 16

Monocytes (become macrophages in tissue)

Question 17

Lymphocyte differentiated in bone marrow

Answer 17

B-cells

Question 18

Lymphocyte differentiate in thymus

Answer 18

T-cells

Question 19

Leukocytes not usually found in blood

Answer 19

Plasma Cells, Mast Cells, Macrophages, Dendritic cells, follicular dendritic cells

Question 20

After stimulation by appropriate target/antigen, all lymphocytes undergo ______

Answer 20

Clonal Expansion

Question 21

Cells that are important for presenting antigen for B-cells

Answer 21

Follicular Dendritic Cells

Question 22

CD3, CD19

Answer 22

T-cells, B-cells

Question 23

Primary (Generative) Lymphoid tissues

Answer 23

Bone Marrow, Thymus

Question 24

Secondary (peripheral) Lymphoid Tissues

Answer 24

Spleen, lymph nodes, Tonsils, MALT

Question 25

Tertiary (ectopic) Lymphoid tissue

Answer 25

Pathology associated

Question 26

Primary lymphoid tissue generates mature naive lymphocytes from immature progenitor cells in this process

Answer 26

Lymphopoiesis

Question 27

Primary location of plasma cells

Answer 27

bone marrow

Question 28

Provide an environment for target/antigen focusing and serve as a storage depot for mature lymphocytes

Answer 28

Secondary Lymphoid tissues

Question 29

Location of B-cells in lymph node

Answer 29

Outer cortex arranged into follicles w/ follicular dendritic cells

Question 30

Location of T-cells in lymph node

Answer 30

interdigitating paracortex with high endothelial venules

Question 31

Samples the mucosal fluids for paticulates, bacteria, and viruses.

Answer 31

MALT

Question 32

In the spleen, capillary sinuses lined with phagocytic endothelium and macrophages that act as a filter and capture antigens

Answer 32

Red Pulp

Question 33

In the spleen, lymphocytes

Answer 33

White Pulp

Question 34

Lymphoid-vascular interface in the spleen

Answer 34

Marginal zone

Question 35

How do T and B-cells organize into their respective territories in lymph nodes and the spleen?

Answer 35

Respond to different chemokines that bind to receptors on their cell surface

Question 36

Antigen stimulate follicle

Answer 36

Germinal center

Question 37

Support high levels of lymphocyte extravasation from the blood

Answer 37

High endothelial venules

Question 38

T>B

Answer 38

peripheral blood, thoracic duct, lymph nodes, thymus

Question 39

T=B

Answer 39

spleen

Question 40

B>T

Answer 40

bone marrow, peyer's patch