8 HIV Flashcards
(20 cards)
List the 3 major blood borne infections?
Hep B
Hep C
HIV
What is AIDs?
A condition in humans leading to the progressive failure of the immune system
What cells does HIV infect?
T cells
What is an opportunistic infection?
An infection that occurs in someone with a compromised immune system
List 3 opportunistic infections that occur in HIV patients
Oral candidiasis
Kaposi Sarcoma
PCP
What fungus causes oral candidiasis?
Candida Albicans
What does a PCP x ray look like?
Consolidations
What group of virus in HIV?
Group 6
ssRNA and RT
What is a capsid?
the protein capsid surrounding the genome
What enzymes are present in HIV?
Intergrase
Protease
Reverse transcriptase
What are the different ways of HIV transmission?
Sexual contact
Transfusion
Contaminated needles
Perinatal transmission
What is the CD4 count of stage I HIV?
more than 500
What is an Aids defining CD4 count?
Less than 200
What factors affect HIV transmission?
Type of exposure
Viral load
Condom use
Breaks in skin, STI, inflammation
What diagnostic tests are there for HIV?
Antibodies for the Ag and Ab
When is PCR used?
Not used for initial HIV testing but for follow up treatment
What different HIV therapies are there?
Protease inhibitor
Intergrase inhibitor
Reverse transcriptase inhibitor
What is the ARVT given to people?
2 nucleoside reverse transcriptase inhibitors
and one of the others
Why are 3 ARVs given?
the virus commonly mutates so resistance develops fast
What is PrEP?
PreExposure prophylaxis, given to people who are at a high risk of HIV
