8. Obesity Flashcards

(49 cards)

1
Q

obesity is associated with

A

incr morbidity and mortality

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2
Q

short term pharmacologic obesity treatment

A

phentermine
benzphetamine
diethylproprion
phendimetrazine

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3
Q

long term pharmacologic obesity treatment

A

orlistat
naltrexone/bupropion
liraglutide
semaglutide
tirzepatide

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4
Q

obesity

A

abnormally high amount of adipose tissue compared with lean muscle mass

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5
Q

obesity is what % over ideal body weight

A

> = 20 %

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6
Q

direct measures of body comp

A

underwater weighting
skin fold measurement
BIA
DEXA

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7
Q

indirect measures of body comp

A

BMI
BSA
IBW
LBW
PNWT

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8
Q

overweight BMI

A

25-29.9

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9
Q

class 1 obesity

A

30-34.9

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10
Q

class 2 obesity

A

35-39.9

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11
Q

class 3 obesity

A

> =40

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12
Q

LBW =

A

TBW - fat weight

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13
Q

LBW compared to IDW

A

LBW > IDW

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14
Q

LBW ~

A

LBW ~ 1.3*IBW

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15
Q

obesity oral abs

A

unchanged

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16
Q

obesity transderma/subQ absorption

A

decr subQ abs

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17
Q

obesity Vd

A

incr Vd for lipophillic drugs

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18
Q

hydrophylic drugs in obese pts

A

little change in Vd

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19
Q

hepatic blood flow in obesity

A

increased hepatic blood flow

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20
Q

what does incr hepatic blood flow mean

A

incr clearance of high extraction ratio drugs

21
Q

high extraction ratio drugs

A

propofol
ketamine
morphine

22
Q

obesity drug half life

A

incr half life due to incr Vd for lipophillic drugs

23
Q

hydrophillic drug clearance

A

incr renal clearance

24
Q

risk of failed regional block

A

1.5* higher when BMI > 30

25
obese pts spinal/epidural dosing
20% less local anesthetic
26
VA lipophiliciity
HIGH iso sevo des LOW
27
which VA is not commonly used in obesity
iso
28
which VA is recommended in obese pts
des
29
sux dosing obesity
TBW
30
vecuronium cisatracurium dosing obesity
IBW LBW
31
roc dosing obesity
IBW LBW
32
pancuronium dosing obesity
higher doses needed
33
best reversal agent for obesity
sugammadex
34
sugammadex obesity dosing
TBW IBW+40%
35
thipental induction dose
LBW
36
thiopental mx dose
TBW
37
dexmedetomidine dose
LBW IBW
38
propofol induction dose
LBW
39
propofol mx dose
TBW
40
etomidate dose
LBW
41
fentanyl dose
LBW
42
most highly lipopphilic opioid
sufentanil
43
sufentanil dosing si
unpredicatble
44
remi dosing
IBW LBM
45
obesitiy is a ________ for VTE
independent risk factor for VTE
46
all obese pts should receive
VTE prophylaxis
47
VTE prophylaxis
SCDs inferior vena cava filters LMWH fondaparinux
48
low VTE risk
LMWH or IPC
49
high VTE risk
LMWH and IPC