8 - Surgical Management of Foot Infection Flashcards

(60 cards)

1
Q

Objectives

A
  • Evaluation and management of foot infections requiring surgical treatment.
  • Current IDSA guidelines for diabetic foot infections.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Indications for surgical interventions

A
  • Abscess
  • Osteomyelitis
  • Gas Producing infection = Medical emergency
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Good info to get in the history

A

o Speed of onset and duration
o Trauma
o Sources of contamination of wound
o Pain – particularly in insensate person
o If likely surgical case, when person last ate or drank

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Good info to get in the ROS

A

o F/C/N/V
o Recent blood glucose

Review drug allergies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Physical exam

A

o Palpable fluctuance, or crepitance
o Lymphangitic streaking
o Mark leading edge of erythema
o Vitals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

X-rays

A

o Look for gas, foreign bodies, signs of osteomyelitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Labs to get

A

o WBC, CMP

o ESR or CRP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

IDSA (infectious disease society of America) Diabetic Foot Infection Classification

A
  • Uninfected
  • Mild
  • Moderate
  • Severe
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Uninfected

A

o Wound without purulence or any manifestations of inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mild

A

o Cellulitis or erythema > 0.5cm to ≤2 cm around ulcer or wound
o Infection is limited to skin or superficial subcutaneous tissue
o No local complications or systemic illness
o ***Should exclude other causes of inflammation (e.g., trauma, gout, acute Charcot, fracture, thrombosis, venous stasis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Moderate

A

o Erythema >2 cm, OR involving deeper structures than skin or subcutaneous tissue (e.g. abscess, osteomyelitis, septic arthritis, fasciitis)
o AND no systemic inflammatory response syndrome (SIRS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Severe

A

Local infection (as described previously) with signs of SIRS as manifested by ≥2 of the following:

  • Temperature > 38°C or 90 beats/min
  • Respiratory rate >20 breaths/min or PaCO2 12,000 or
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

IDSA validation - full thickness

A

This is how often each grade of the IDSA scale leads to a full thickness wound (no deeper):

  • No infection: 88.7%
  • Mild infection: 76.1%
  • Moderate infection: 30.8%
  • Severe infection: 22.2%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IDSA validation - fascia or tendon

A

This is how often each grade of the IDSA scale probes to fascia or tendon (no deeper)

  • No infection: 7.2%
  • Mild infection: 21.1%
  • Moderate infection: 25.0%
  • Severe infection: 11.1%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IDSA validation - bone or joint

A

This is how often each grade of the IDSA scale probes to bone or joint:

  • No infection: 4.1%
  • Mild infection: 2.8%
  • Moderate infection: 44.2%
  • Severe infection: 66.7%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

IDSA validation - bone infection

A

This is how often each grade of the IDSA sale leads to bone infection

  • No infection: 0%
  • Mild infection: 0%
  • Moderate infection: 38.5%
  • Severe infection: 37%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Graph on hospitalization and amputation rates based on the IDSA grade of infection

A
  • No infection: very few hospitalizations, very few amputations
  • Mild infection: 10% are hospitalized, very few amputations
  • Moderate infection: 55% are hospitalized, 45% have amputations
  • Severe infection: 90% are hospitalized, 75% have amputations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Causative organism for cellulitis without open skin lesion

A
  • Staph aureus

- Beta hemolytic strep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Causative organism for infected ulcer, antibiotically naive

A
  • Staph aureus

- Beta hemolytic strep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Causative organism for infected ulcer, previously treated

A
  • Staph aureus
  • Beta hemolytic strep
  • Enterobacter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Causative organism for macerated ulcer due to drainage or soaking

A
  • Pseudomonas

- Polymycrobial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Causative organism for long standing ulcer with prolonged broad spectrum antibiotic use

A
  • Polymycrobial
  • Staph aureus
  • Beta hemolytic
  • Pseudomonas
  • Gram negative rods
  • Resistant bacteria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Causative organism for “fetid foot” - extensive necrosis or gangrene

A
  • Gram positive cocci
  • Gram negative rods
  • Obligate anerobes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Causative organism for osteomyelitis

A
  • Staph aureus

- Pseudomonas (puncture wounds)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Clinical signs of MSSA
o Thick, yellow, purulent drainage
26
Clinical signs of MRSA
o Usually quicker onset of purulent producing infection
27
Clinical signs of Strep
o Deeper red infection than staph and not as purulent
28
Clinical signs of pseudomonas
o Fruity smell | o Green tinge to wound
29
Clinical signs of anaerobes
o Extreme foul smell | o Brown, watery discharge
30
IDSA suggested antibiotics for moderate to severe foot infections with MSSA, streptococcus, enterobacteria and obligate anaerobes
1 = Ampicillin-sulbactam (Unasyn) - This is adequate if low suspicion of pseudomonas 2 = Ertapenem - Once daily dosing, relatively broad spectrum, not active against pseudomonas 3 = Imipenem-cislastin - Very broad spectrum (no MRSA coverage) only use when needed
31
IDSA suggested antibiotics for moderate to severe foot infections with MRSA
Vancomycin
32
IDSA suggested antibiotics for moderate to severe foot infections with pseudomonas aeruginosa
Piperacillin-tazobactam (zosyn) | - TID or QID dosing, but good broad spectrum coverage
33
Case study HPI
o 53 year old female admitted to hospital by PCP for diabetic foot infection o PCP noted larger bulla on plantar right midfoot with foul drainage o Pain on foot and leg o Fever (102 degrees F), chills, nausea, vomiting
34
Case study ROS
``` o Last blood glucose 200-300 o A1c 8-10 o Numbness in hands and feet o Blurred vision secondary to retinopathy o Heart palpitations for 2 days ```
35
Case study PMHx
o Type 2 diabetes | o Renal failure with dialysis
36
Case study physical exam
``` o Vascular: pedal pulses palpable o Neuro: diminished o Foot: hot, swollen, erythematous foot o Derm: large bulla the width of the plantar arch with gray/black in color with small opening centrally. Erythema to surrounding tissue, no purulent drainage o Musculoskeletal: pain with palpation ``` X-ray o Gas gangrene in the medial arch o Make sure it isn’t tracking up into the leg (this stays mostly in the arch, medial to lateral) Culture o Either culture drainage in the ER or do it in the OR
37
Labs yesterday and labs today
``` - Labs yesterday (CRP, ESR, WBCs) o WBC = 29.5 (10 is normal) o H/H = 10.6/31 o Bun/Cr = 86/6.2 o Blood glucose = 294 o Albumin = 3.2 o C-reactive protein = 24.1 (1 or less is normal) ```
38
Treatment
Emergency I & D o Infections will more commonly track up tendons o Less commonly it will track across the arch o Can see the plantar fascia o Use bag of 300 mL of saline and wash it out with pressure lavage
39
Dressing
o Pack the wound o Do not close the wound because it would increase an anaerobic environment o Let it drain then go back a few days later
40
Cultures
``` o Staph aureus o Strep (GBS) o Bacteroides o MRSA o Enterobacter ```
41
Repeat I & D
o Back to OR for repeat o Continued purulent drainage o Intraoperative findings = necrotic tissue found within wound o Purulent drainage from multiple deep pockets o Wound VAC applied in OR
42
Management going forward
o Diabetes o Living situation with help o WB, antibiotics
43
Discharge from hospital
o Patient sent to SNF for wound vac therapy and 4 weeks IV abx (vanc, zosyn) per ID recommendation o Wound eventually healed
44
CASE STUDY 2
o 51 year old male presents to clinic with ulcer plantar left hallux o Went on fishing trip 1 month ago, ulcer formed from wet, rubbing boots o 10 days ago noticed erythema and edema o 4 days ago went to ED and was put on ED
45
Case study PMHx
o T2D, HTN o Heart murmur o High cholesterol, colon cancer hx
46
Case study social
o Denies tobacco, alcohol, drug use | o Counselor at prison system
47
Case study ROS
o Denies fever, chills, nausea, vomiting o Blood glucose around 120, does not check often due to o Some numbness and tingling in the feet o Does not feel like feet are hot or cold (vascular) o Denies claudication o Had ulcers before? Did they heal?
48
Case study physical exam
o Pedal hair present o Pedal pulses are not palpable but are biphasic with Doppler and pedal hair is present o Cannot feel monofilament (2/10) o Size of ulcer is 2 mm in diameter o Derm: erythema noted to lef hallux with slight purpule discoloration o Ulcer plantar hallux IPJ with yellow fibrotic base o Edema present to hallux and foot o Musculoskeletal: ROM is somewhat limitied to 1st MPJ, pain to palpation of the hallux, no fluctuance or crepitus
49
Case study initial visit
o Purple discoloration from infection o Get x-ray, take culture, get bloodwork o Antibiotics are not currently helping o Vascular studies (did not get them because circulation was pretty good) o Offloading (total contact cast, boot, post-op shoe, cutout over 1st ray) o Dress the wound, does not meet criteria to put in the hospital
50
Cultures
o Group G strep o MSSA Bactrim o Bactrim only covers staph and usually MRSA o Bactrim does NOT cover strep very well – not great
51
X-rays
o No gas present | o No erosive changes in bones (no osteo)
52
1 week later
o Toe started turning gray 2 days after being seen o Presents with completely black toe o Needs amputation right away o Progressed so quickly so be suspicious of necrotizing fasciitis
53
Hospital
o Admit to hospital o X-rays o Labs o Amputation
54
Labs at hospital
o WBC = 12.7 o Sed rate = 100 o CRP = 7.5 o AbA1c = 8.1
55
Treatment
o Hallux amputation performed o Cultures came back as skin flora o Patient send home non-weight bearing
56
4 weeks post op
o Sutures removed because they were loose o Minimal drainage o No pain o Would like to go back to work
57
6 weeks post op
o Patient called in stating he can see bone o Instructed to use betadine and call if redness or signs of systemic o Wound came open 1-2 weeks after going back to work
58
How to manage now
o X-rays o 1st ray amputation or partial first ray amputation o Admit to hospital o MRI to see extent of bone involvement (1st met head is destroyed, Edema goes back to base of 1st met head, Infectious disease wanted the whole 1st ray to be gone) o Biomechanics (If you take off the whole first ray, he will have no attachment for Lis francs TA, more pressure on other metatarsals)
59
2 weeks later
Healing well at this time
60
Case study 3
- 52-year-old diabetic male with new ulcer plantar 2nd metatarsal head - Chills nausea - Vascular -= DP palpable, PT not, glucose 765 - 2nd ray is already missing - High BP, high pulse, high respirations - Admitted to hospital right away - X-rays – Soft tissue gas