Anatomy endocrine pancreas

Question 1

What are hormone secreting cells in the gut called? What are the 2 variations of this cell?

Answer 1

Isolated hormone secreting cells of the GI tract

open type secrete on the surface - may be reactive to gut contents

closed type deep to surface - receptive to changes in tissue environment

Question 2

How would you identify the enteroendocrine cells in an electron microscopy?

Answer 2

cells with granules

Question 3

Islets of Lagnerhans: What % of cells do they make and what portion of blood supply?

Answer 3

1-2% volume of the organ

20% of the blood supply

Question 4

In the pancreas, what cells are exocrine? Endocrine?

Answer 4

acinar cells and acinar ducts are exocrine

islet cells are endocrine

Question 5

What do islet cells differentiate from?

Answer 5

cells adjacent to the acinar ducts

Question 6

Pancreas is retroperitoneal T/F?

Answer 6

TRUE

tail of pancreas is NOT retroperitoneal

Question 7

List the distribution of islets cells throughout the pancreas (which part has what % of islets?)

Answer 7

25% in head
25% uncinate process
20% body
30% tail

Question 8

What cells make what endocrine hormones in the pancreas? Which one is present in the largest numbers?

Answer 8

glucagon alpha cells
insulin beta cells (largest percentage)
somatostatin delta cells

Question 9

Blood supply of pancreas

Answer 9

splenic and superior and inferior pancreaticoduodenal arteries
veins of splenic and superior mesenteric portal

Question 10

Innervation of pancreas

Answer 10

sympathetic - abdominopelvic splanchnic

parasympathetic - vagal