REVISION CONCEPTS Flashcards

1
Q

What is the difference between the coding strand versus the RNA strand?

A
  • The Ts in the coding strand are replaced by Us in the RNA strand
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2
Q

Which direction is the template strand read in and why?

A
  • A 3’–> 5’ direction

- Because RNA must be synthesized in a 5’–> 3’ direction

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3
Q

Which enzyme synthesizes RNA and does it need a primer?

A
  • RNA polymerase

- Does not need a primer

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4
Q

What are the 3 stop codons?

A
  • TAG (UAG)
  • TAA (UAA)
  • TGA (UGA)
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5
Q

What are the nonpolar, aliphatic R group amino acids?

A
  • MAGLIVP
  • Methionine
  • Alanine
  • Glycine
  • Leucine
  • Isoleucine
  • Valine
  • Proline
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6
Q

What are the nonpolar aromatic R groups?

A
  • Phenylalanine
  • Tyrosine
  • Trptophan
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7
Q

What are the Polar, uncharged R groups?

A
  • Glutamine
  • Asparagine
  • Cysteine
  • Threonine
  • Serine
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8
Q

What are the positively charged R groups?

A
  • Histidine
  • Arginine
  • Lysine
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9
Q

What are the negatively charged R groups?

A
  • Aspartate

- Glutamate

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10
Q

When the pH>pka of the functional group, which form dominates?

A
  • Deprotonated form dominates
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11
Q

What is pKa defined as?

A
  • The pH at which a chemical species will accept or donate a proton
  • Low pKa means stronger acid and higher Pr of donating proton
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12
Q

When the pH

A
  • The protonated form (pretty much saying in an acidic environment, there will be lots of H+)
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