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Maddy - CPR I - some pharm > Parasympathetic Autonomics > Flashcards

Parasympathetic Autonomics Flashcards

1
Q

M3 and M2 receptors - sphincter muscle of iris

A

contraction (miosis)

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2
Q

M3 and M2 receptors - ciliary muscle of eye

A

contraction for near vision

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3
Q

M3 and M2 receptors - lacrimal glands of eye

A

increased secretion

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4
Q

M2 receptor - SA node

A

decreased HR

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5
Q

M2 receptor - atria of heart

A

decreased contractility and shortened AP duration

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6
Q

M2 receptor - AV node

A

decrease in conduction velocity, AV block

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7
Q

M2 receptor - His-purkinje system

A

little effect

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8
Q

M2 receptor - ventricles of heart

A

slight decrease in contractility

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9
Q

muscarinic receptors - blood vessels

A

no innervation

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10
Q

M3 receptor - endothelium

A

activation of NO synthase

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11
Q

M3 and M2 receptors - tracheal and bronchial smooth muscle

A

contraction

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12
Q

M3 and M2 receptors - bronchial glands

A

stimulation

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13
Q

M3 and M2 receptors - motility and tone of stomach and intestines

A

increased

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14
Q

M3 and M2 receptors - sphincters of stomach and intestines

A

relaxation

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15
Q

M3 and M2 receptors - secretions in stomach and intestines

A

stimulation

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16
Q

M3 receptor - detrusor muscle of bladder

A

contraction

17
Q

M3 receptor - trigone and sphincter of bladder

A

relaxation

18
Q

M3 and M2 receptors - salivary glands

A

increase potassium and water secretion

19
Q

M1 receptors

  • location
  • what GCPR
  • mechanism
A
  • nerves
  • Gq
  • IP3 and DAG cascade
20
Q

M2 receptors

  • location
  • what GCPR
  • mechanism
A
  • heart, nerves, smooth muscle
  • Gi
  • inhibition of cAMP and activation of K+ channels
21
Q

M3 receptors

  • location
  • what GCPR
  • mechanism
A
  • glands, smooth muscle, endothelium
  • Gq
  • IP3 and DAG cascade
22
Q

M4 receptors

  • location
  • what GCPR
  • mechanism
A
  • CNS
  • Gi
  • inhibition of cAMP
23
Q

M5 receptors

  • location
  • what GCPR
  • mechanism
A
  • CNS
  • Gq
  • IP3 and DAG cascade
24
Q

NN receptors

  • location
  • mechanism
A
  • postganglionic cell body, dendrites, CNS

- Na+, K+ depolarizing ion channel

Maddy - CPR I - some pharm (25 decks)

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