Molecules of Life Flashcards
1
Q
Biomedical Importance of Water
A
- Water is a reactant in metabolic and enzymatic reactions.
- Water regulated by Anti-Diuretic Hormone (Vasopressin) and evaporative loss
- Body Water function of age, body mass, and body fat
- Body water mass declines with age
2
Q
Molar Concentration of Water
A
55.6 M
3
Q
Dissociation Constant of Water
A
1x10^-14
4
Q
Henderson-Hasselbalch Equation
A
pH = pKa + log [A-]/[HA]
5
Q
Why can aspirin be easily absorbed into the blood from the stomach?
A
At pH 1.5, it is protonated and neutral charged
6
Q
Composition of Buffers
A
Mixture of a weak acid and its conjugate base
7
Q
Physiological Phosphate Buffer
A
H2PO4- HPO42-
8
Q
Bicarbonate Buffer
A
CO2 + H20 H2CO3 (E: carbonic anhydrase)
H2CO3 H+ + HCO3-
9
Q
How is [CO2] measured in the body?
A
pCO2 (alveolar air) * 0.03 mM/mm Hg gives arterial plasma concentration
10
Q
Three Ways to Regulate pH
A
H+ + HCO3- H20+CO2 (Lungs)
H+ + HPO42- H2PO4- (kidneys)
H+ + NH3 NH4+ (kidneys)
11
Q
Isohydric Transport
A
Transport of CO3 without generating a change in blood pH
