Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Gastro Review > GI CA@ > Flashcards

GI CA@ Flashcards

1
Q

Esoph CA T1-2 tx

A

Esophagectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Esoph CA T3-4 tx if resectable

A

Chemo then surg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T staging levels for esoph CA

A 
T0 = HGD
T1 = LP, submucosa
T2 = MP
T3 = adventitia
T4 = adjacent structures
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which pts require gastric CA screening program?

A

None - not IM, not atrophic gastritis, not FAP or Lynch, not partial gastrectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a Spindle cell neoplasm?

A

A type of GIST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

High risk GIST tx?

A

Surg + 36 mon of imatinib if resectable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which gene is affected earliest in transition to CRC?

A

APC gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which Lynch screening starts at age 20?

A

Colonoscopy every 1-2 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which 4 tests to get for Lynch starting at age 30?

A
  1. TVUS Q1yr
  2. EGD with antral bx
    Q2-3yrs
  3. UA Q1yr
  4. Pelvic with PAP Q1yr
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hereditary diffuse gastric CA with mutation in which gene?

A

CDH1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What else AW CDH1 mut?

A

Lobular breast CA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Rt sided CRC with mucinous features and tumor infiltrating LCs classic for what?

A

MMR gene mut in Lynch pts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If polyp removed with AC within it - which features would req surg?

A
  • G3 histo (poorly diff)
  • <1mm margins
  • Piecemeal resection
  • Lymph/vasc invasion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T1 Gastric NET AW which condition?

A

Atrophic gastritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T2 gastric NET (carcinoid) AW which conditions?

A

ZES and MEN1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

T3 gastric NET AW which condition?

A

None

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which type of gastric NET Is worst and needs surg?

A

T3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Asian M&F age for HCC screening in HBV?

A 
M = 40
F = 50
19
Q

Nodule <1 cm mgmt in cirrhotic?

A

Repeat US in 3 months

20
Q

BRCA2 gene causes which CAs?

A

Breast
Ovarian
Panc

21
Q

List MC to LC GI CA.

A

CRC > Panc > Liver > Stomach > Esophagus > SI

22
Q

Best tx for T3N0 AC of esophagus?

A

Chemotherapy followed by surgery

23
Q

What are sxs of plummer vinson and what is it associated with?

A

IDA, Dysphagia due to webs, angular chelitis, glossitis - AW esophageal SCC so get annual screening

24
Q

Associated conditions wt PVS?

A

celiac, RA, thyroiditis, pernicious anemia

25
Q

If early MALToma, what is rate of cure with HP tx?

A

75%

26
Q

If pt dx with MALT, what should be done for workup?

A

CT CAP, EGD with mapping, BM bx, EUS

27
Q

What is the best mgmt of gastric GIST with high risk features?

A

Surgery followed by 36 months of imatinib

28
Q

What are GIST high risk features?

A

Size > 10 cm, Size > 5 cm with mitotic rate of > 5/50 hpf, mitotic rate > 10/50 hpf

29
Q

Risk of panc AC in the following:

  1. Hereditary Panc
  2. PJS
  3. Familia atypical mole melanoma syndrome
  4. Lynch
  5. FAP
A
  1. HP - 40%
  2. PJS - 36%
  3. FAMMS - 17%
  4. Lynch - 3.6%
  5. FAP - 3x risk c/t gen pop
30
Q

What is the earliest mutation on the road to CRC?1

A

APC - leads to adenomatous changes

31
Q

List Lynch screening recs.

A
  1. CRC every 1-2 years starting age 20
  2. EM sampling starting age 30
  3. Annual TVUS at age 30
  4. EGD with antral biopsies every 2-3 yrs starting age 30
  5. UA annually beginning age 30
32
Q

CDH1 mutation inc risk of what?

A

Gastric and lobular breast CA

33
Q

When you do a polypectomy and there is surgery within the polyp, what factors increase risk of recurrent CRC and indicate a need for surgery?

A

Grade 3 histo (poorly differentiated)
< 1 mm disease free margin
Piecemeal resection
Lymphatic or vascular invasion

34
Q

Which tumors stain + for CD117?

A

GIST

35
Q

What is size cut off for surgery in GISTs?

A

> 2 cm

36
Q

Mass with “nests of endocrine cells”

A

NET

37
Q

Three types of Carcinoids.

A

Type 1 - well differentiated, AW chronic gastritis - can do EMR
Type 2 - AW ZES and MEN1
Type 3 - NOT AW hypergastrinemia, poor prognosis

38
Q

Difference between carcinoid and NET?

A

Carcinoid is a type of NET

39
Q

When choosing enteral stenting vs GJ tube for gastric cancer, at what point is GJ better than stenting?

A

If pt expected to live > 2 months.

40
Q

Enteropathy associated T cell lymphoma is AW which dz?

A

Celiac dz

41
Q

T/F: All pts with HBV who have a FH of HCC should be screened for HCC, even without cirrhosis.

A

True

42
Q

Name the 3 HR features of PCLs.

A

Size > 3 cm, solid component, dilated PD - EUS if 2/3

43
Q

BRCA2 cancers

A

Breast, ovarian, pancreas (BRCA2 BOP)

Gastro Review (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions