8.1 Placenta Flashcards

1
Q

when does the placenta begin to develop?

A

2nd week

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2
Q

is the placenta a fatal membrane?

A

yes, a specialised one

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3
Q

what’s produced by the syncytiotrophoblast? function?

A

hCG
maintains corpus luteum and steroid hormones for a viable pregnancy

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4
Q

which cell mass develops into the placenta?

A

outer

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5
Q

relationship of embryo+syncytiotrophoblast to maternal endometrium at end of implantation

A

integral

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6
Q

why does the yolk sac disappear?

A

primitive gut development pinches it off

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7
Q

why does the amniotic cavity enlarge?

A

fetus enlarges

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8
Q

formation of amniochorionic membrane

A

amniotic and chorionic membranes fuse

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9
Q

‘waters breaking’

A

break of amniochorionic membrane releasing amniotic fluid, signals start of labour

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10
Q

why don’t the maternal blood and feral blood circulations never mix?

A

separate genetics

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11
Q

why do the metabolic needs of the foetus increase?

A

fatal brain grows so needs more E (glucose)

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12
Q

decidua function

A

manages depth of invasion of implantation, balanced against aggression from enzymes released from syncytiotrophoblast

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13
Q

why can ecptoic pregnancies implant deeply?

A

no decidua so cant control depth of invasion

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14
Q

cotyledons

A

functional units containing chorionic villi (allow transport)

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15
Q

why do chorionic villi become thinner by end of pregnancy? how do they thin?

A

metabolic requirements of fetus increase
lose most of cut-trophoblast layer (small amount left is for stem cells)

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16
Q

blood supply to and from fetes

A

1 umbilical vein: oxy blood from placenta to fetus

2 umbilical arteries: deoxy blood from fetus to placenta

17
Q

when does placenta take over corpus luteum’s function of producing steroid hormones?

A

end of first trimester

18
Q

pregnancy specific hormone

A

hCG

19
Q

trophoblast diseases upregulate hCG. Give 2 examples

A

-molar pregnancy
-choliocarcinoma

20
Q

overall influence of placental hormones on maternal metabolism

A

subvert maternal physiology to provide for fetus, at expense of mother

21
Q

why does the mother’s appetite increase?

A

progesterone, release E from mothers fat stores, and take in more glucose for brain E

22
Q

side effect of glucose availability for fetus

A

insulin resistance in mother

23
Q

what can limit uteroplacental circulation at end of pregnancy?

A

contractions

24
Q

is passive immunity endo or exocytosis?

A

endocytosis

25
Q

teratogens

A

substance capable of disturbing fatal embryonic development

26
Q

FAS

A

fetal alcohol syndrome

27
Q

ARND

A

alcohol related neurological delay

28
Q

effect of thalidomide

A

damages endothelial vasculogenesis so limbs cant develop

29
Q

main system of fetal body susceptible to structural defects after embryonic period

A

CNS