Biology: Peripheral + Central Sensitisation Flashcards

1
Q

Define pain

A
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2
Q

Name the 2 aspects of pain

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3
Q

Define nociception

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4
Q

What is threshold level of activation for acute pain?

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5
Q

How is acute pain a protective mechanism?

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6
Q

What can hypersensitivity be a consequence of?

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7
Q

Define Allodynia

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8
Q

Define Hyperalgesia

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9
Q

Changes in nociceptive system in peripheral system

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10
Q

Changes in nociceptive system in central sensitisation

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11
Q

What is inflammatory soup + how is it generated?

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12
Q

How do factors work?

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13
Q

Prostaglandin sensitisation pathway

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14
Q

What is NGF + what is its function?

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15
Q

What is the NGF receptor + where is it present?

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16
Q

What are ASICs + how is it activated?

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17
Q

How is ASIC3 inhibited?

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18
Q

How does ATP activate nociceptor?

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19
Q

Describe bradykinin sensitisation pathway

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