Antigotosos Flashcards

1
Q

numero uno en tx de gota aguda

A

Colchicina

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2
Q

EA de la Colchicina

A

Diarrea en agua de arroz

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3
Q

Tiempo en aliviar la artritis gotosa de la colchicina

A

12-24 inhibe la migracion de los linfocitos y fagocitos tx criss gota y profilaxis prolongada

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4
Q

tx alopurinol

A

num 1 en gota cronica entre criss agudas

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5
Q

mecanismo de accion del alopurinol

A

inhibe la XO y se degrada a aloxantina

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6
Q

usado en pacientes con quimio ca hematologico por disminuir el urato plasmatico

A

alopurinol

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7
Q

medicamento que si no se administra con AINE o Colchicina causa precipitacion de la gota

A

alopurinol

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8
Q

inhibidor selectivo de XO

A

Febuxostat

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9
Q

usado en Hiperuricemia cronica mas efectivo que el alopurinol

A

Febuxostat

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10
Q

usado en pediatricos con leucemia

A

Rasburicasa

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11
Q

la Rasburicasa de que se deriva

A

Saccharomyces Cerevisae

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12
Q

la rasburicasa ctaliza el acido urico a

A

alantoina EA hemolisis en deficiencia de G6FD

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13
Q

Menciona los uricosuricos

A

Probenecid Sulfinpirazona Benzbromarona

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14
Q

inhibe el URAT1

A

Probenecid

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15
Q

EA probenecid

A

litiasis renal , exantema , sd nefrotico

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16
Q

indicado cuando el alopurinol y febuxostan estan CI

A

Probenecid

17
Q

indispensable para tener volumenes altos de orina y se inhibe por silicatos

A

Probenecid

18
Q

uso en pacientes con gota tofacea o crisis de gota

A

Sulfinpirazona

19
Q

tambien inhibe URAT1 eficiente en px con IRy CI en nefrolitiasis

A

Benzobromarona

20
Q

AINES que inhiben prostaglandinas usados en la gota

A

indometacina sustitucion por colchicina y Sulindaco, Oxaprozina disminuye el acido urico serico