parvoviridae

Question 1

general characteristics of parvoviridae

genetic material

enveolped?

viruses

Answer 1

ssDNA

Nonenveloped (STABLE)

canine parvo

feline panleukopenia

porcine parvo

human parvo

Question 2

canine parvovirus

1. types of dz virus causes
2. method of transmission
3. zoonotic?
4. does it change/recombine/mutate
5. distribution
6. diagnosis
7. differential diagnosis
8. control

Answer 2

1. enteritis, myocarditis
2. fecal oral/fomites/ contact/ req dividing cells in S phase for replication (start in lymphoid tissue). dev viremia and virus will enter bone marrow, lymph tissue, crypt cells
3. no
4. can mutate- used to be a feline dz that mutated into canine parvo. likewise, can be transm to cats
6. smell, EM, fecal HA, ag capture ELISA, pcr on feces
7. corona, rota
8. vaccs!!! assoc with loss of maternal abs

Question 3

feline panleukopenia

1. types of dz virus causes
2. method of transmission
3. zoonotic?
4. does it change/recombine/mutate
5. distribution
6. diagnosis
7. differential diagnosis
8. control

Answer 3

1. sudden fever, death, depression, enteric v/d
2. trans via indirect (envt) or direct contact, body secretions, fecal - oral, in utero
3. not zoonotic
4. easily mutates- changed to canine parvo
6. virus isolation, fecal pcr, ELISA (can use canine test, but not as sensitive)
7. feline enteric coronavirus, rota, reo
8. vaccinate

Question 4

porcine parvovirus (SMEDI?)

1. types of dz virus causes
2. method of transmission
3. zoonotic?
4. does it change/recombine/mutate
5. distribution
6. diagnosis
7. differential diagnosis
8. control

Answer 4

1. affinity for actively dividing cells ex fetus so causes abortions in early prgnancy (<70 d)– (different from prrsv- late term abortions).
2. transmission- fecal oral, transplacental, semen, ingestion, aerosol
3. not zoonotic
5. worldwide
6. diagnosis via IFA on mummified piglets, HA (will agglutinate), virus isolation on fetus, pcr
7. prrsv
8. vaccinate, management