Cirrhosis Flashcards
1
Q
Description: What is cirrhosis?
A
- End stage chronic liver disease which results in irreversible liver damage
2
Q
Aetiology/ Risk factors: What are the different causes of cirrhosis? (11)
A
Causes:
- Cryptogenic (unknown cause) – most common
- Alcohol
- Autoimmune liver disease (3)
- Hepatitis B (chronic)
- Hepatitis C (chronic)
- Haemochromatosis (genetic)
- Alpha-1-antitrypsin deficiency
- Wilson’s disease
- Obesity (Diabetes mellitus)
- Drugs (amiodarone, methotrexate – MXT)
- Immune mediated liver disease
3
Q
Pathology: State the pathology that goes on in the liver during cirrhosis
A
- Replacement of normal liver tissue to nodules of hepatocytes and fibrous tissue
