Gynecopathology Flashcards

Second Midterm (Semester 2)

1
Q

Endometriosis may occur in the colon

a. True
b. False

A

a. True

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2
Q

True for peau d’orange

a. Often occurs in estrogen-receptor positive breast cancers
b. Happens in intraductal carcinoma
c. Shows good prognosis
d. Occurs due to a sclerotizing adenosis
e. Is a sign of invasive breast cancer

A

e. Is a sign of invasive breast cancer

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3
Q

Typical histological features of ovarian serous papillary carcinoma (2 answers):

a. High mitotic count
b. Salt and pepper chromatin structure
c. Small round blue cells
d. Psammoma body

A

a. High mitotic count

d. Psammoma body

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4
Q

Call-Exner bodies are typical for

a. Serous cystadenocarcinoma
b. Dysgerminoma
c. Granulosa cell tumor
d. Sertoli cell tumor
e. Malignant teratoma

A

c. Granulosa cell tumor

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5
Q

Premalignant lesion in the breast:

a. Adenosis
b. LCIS
c. Apocrine metaplasia
d. Florid ductal hyperplasia

A

b. LCIS

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6
Q
Which of the following tumor types can NOT occur in the testes?
a. Teratoma
b. Krukenberg tumor
c. Chriocarcinoma
d. Yolk sac tumor
Seminoma
A

b. Krukenberg tumor

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7
Q

Nodular hyperplasia of the prostate is a pre-cancerous

a. True
b. False

A

b. False

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8
Q

Juvenile papillomatosis of the breast is a malignant lesion

a. True
b. False

A

b. False

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9
Q

Krukenberg tumor is a bilateral primary ovarian tumor

a. True
b. False

A

b. False

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10
Q

Typical for condyloma accuminatum (2 answers)

a. Macroscopically it is only papillary
b. Koilocytosis
c. Has a berry-like appearance
d. Is caused by an infection by HBV

A

a. Macroscopically it is only papillary

b. Koilocytosis

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11
Q

Invasive ductal carcinoma of the breast grows in “indian file”

a. True
b. False

A

b. False (lobular is)

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12
Q

The most serious acute complication of extrauterine gravidity:

a. Intra-abdominal abscess
b. Choriocarcinoma
c. Torsion of the ovary
d. Intra-abdominal bleeding

A

d. Intra-abdominal bleeding

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13
Q

Histological features of breast cancer indicating typically poor prognosis (2 answers):

a. Lymphovascular invasion
b. High mitotic count
c. Intense mucin production
d. High rate of tubulus formation

A

a. Lymphovascular invasion

b. High mitotic count

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14
Q

The most common histological type of ovarian carcinoma:

a. Brenner tumor
b. Clear cell carcinoma
c. Mucinous cystadenocarcinoma
d. Serous cystadenocarcinoma
e. Endometroid carcinoma

A

d. Serous cystadenocarcinoma

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15
Q

Which microscopical features are characteristic for simplex endometrial hyperplasia?

a. Papillary epithelium without atypia
b. Cystic glands, proliferative epithelium without atypia
c. Confluent glands with necrosis
d. Normal glands without mitoses

A

b. Cystic glands, proliferative epithelium without atypia

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16
Q

Which clinical features rise the possibility of inherited BRCA mutation (2 answers)?

a. Metachronous breast- and ovarian cancer
b. Postmenopausal lobular carcinoma of the breast
c. Positive familial history for breast cancer
d. Congenital ovarian teratoma

A

a. Metachronous breast- and ovarian cancer

c. Positive familial history for breast cancer

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17
Q

The most common neoplasm of the uterine corpus:

a. Adenoma
b. Leiomyoma
c. Adenocarcinoma
d. Leiomyosarcoma

A

b. Leiomyoma

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18
Q

Predispose to endometrial adenocarcinoma:

a. Extrauterine gravidity
b. Postmenopausal estrogen replacement therapy
c. HPV infection
d. Leiomyoma

A

b. Postmenopausal estrogen replacement therapy

19
Q

The first site of metastases from uterine cervix cancer

a. Inguinal lymph nodes
b. Paraaortic lymph nodes
c. Omentum
d. Pelvic lymph nodes

A

d. Pelvic lymph nodes

20
Q

Typical symptom of mastitis carcinoma:

a. Retraction of the mamilla
b. Palpable lump in the breast
c. Bloody discharge from the mamilla
d. Peau d’orange sign

A

d. Peau d’orange sign

21
Q

Which cell type composes the mole disease?

a. Endometrial glandular epithelium
b. Decidual stroma cell
c. Trophoblast
d. Smooth muscle cell of the myometrium

A

c. Trophoblast

22
Q

The most common malignant tumor of the breast is the so-called “not otherwise specified” invasive ductal carcinoma

a. True
b. False

A

a. True

23
Q

Typical locations of distant metastases of breast cancer:

a. Heart, lung, brain
b. Ovary, liver, spleen
c. Brain, adrenal, thyroid
d. Brain, lung, bones, liver

A

d. Brain, lung, bones, liver

24
Q

The Paget-disease of the breast:

a. Breast cancer with exulceration of the skin
b. Breast cancer with diffuse lymphogenic invasion
c. In situ carcinoma spreading into the epidermis of the nipple
d. In situ squamous cell carcinoma of the skin of the breast

A

c. In situ carcinoma spreading into the epidermis of the nipple

25
Q

Breast cancer with good prognosis

a. Mucinous carcinoma
b. Invasive ductal carcinoma grade 1
c. Metaplastic carcinoma
d. Invasive micropapillary carcinoma

A

a. Mucinous carcinoma

26
Q

True for prostate hyperplasia

a. Common in young males
b. It affects mainly the periurethral parenchyma
c. Caused by high level of testosterone
d. It is a precancerous condition

A

b. It affects mainly the periurethral parenchyma

27
Q

Lobular carcinoma of the breast is frequently bilateral

a. True
b. False

A

a. True

28
Q

Testicular tumor with benign behavior:

a. Seminoma
b. Yolk sac tumor
c. Teratoma of the adults
d. Teratoma of the childhood

A

d. Teratoma of the childhood

29
Q

Which ovarian tumor can cause pseudomyxoma peritonei?

a. Mucinous cystadenocarcinoma
b. Dermoid cyst
c. Brenner tumor
d. Serous cystadenofibroma

A

a. Mucinous cystadenocarcinoma

30
Q

Condyloma latum is caused by the most infectious HPV strands

a. True
b. False

A

b. False (latum is caused by Treponema pallidum - Syphilis)

31
Q

HPV virus causes (2 answers)

a. Cervical carcinoma
b. Condyloma latum
c. Verruca vulgaris
d. Trachoma

A

a. Cervical carcinoma

c. Verruca vulgaris

32
Q

Endometriosis of the colon can mimic cancer:

a. True
b. False

A

a. True

33
Q

Cryptorchidism increases the risk of developing testicular cancer

a. True
b. False

A

a. True

34
Q

What causes the “chocolate cyst”?

a. Endometriosis of the ovary
b. Anemic infarction of the ovary
c. Bleeding of the dermoid cyst in the ovary
d. Hemorrhagic infarction of the ovary

A

a. Endometriosis of the ovary

35
Q

The most common benign tumor of the breast is phyllodes tumor

a. True
b. False

A

b. False (Fibroadenoma is)

36
Q

True for prostate cancer (2 answers)

a. Frequent vertebral metastasis
b. Its precancerosis is prostate hyperplasia
c. Its ancient name is “hypernephroma”
d. Generally derives from the peripherial parenchyma

A

a. Frequent vertebral metastasis

d. Generally derives from the peripherial parenchyma

37
Q

Most common benign changes of the breast (2 answers)

a. Fibrocystic breast disease
b. Juvenile papillomatosis
c. Fibroadenoma
d. Galactocele

A

a. Fibrocystic breast disease

c. Fibroadenoma

38
Q

Risk factors for breast cancer (2 answers)

a. Contraceptives
b. Premenopausal breast cancer in close relative
c. Atypical ductal epithelial hyperplasia
d. Anti-estrogen therapy

A

b. Premenopausal breast cancer in close relative

c. Atypical ductal epithelial hyperplasia

39
Q

Germinal ovarian tumor (2 answers)

a. Dysgerminoma
b. Teratoma
c. Androblastoma
d. Serous cystadenocarcinoma

A

a. Dysgerminoma

b. Teratoma

40
Q

Most common tumors in the ovary are the germ cell tumors

a. True
b. False

A

b. False (surface epithelium are the most common)

41
Q

HPV 16 and 18 play a role in the development of cervical carcinoma

a. True
b. False

A

a. True

42
Q

Inflammation of the glans:

a. Phallitis
b. Glansitis
c. Balanitis
d. Penitis

A

c. Balanitis

43
Q

Breast cancer is the most common cancer in women, and is also the cancer with the highest mortality.

a. True
b. False

A

b. False (breast highest incidence, lung highest mortality)

44
Q

Dysgerminoma of the ovary is identical with seminoma of the testis

a. True
b. False

A

a. True