Hepatology 2

Question 1

Measures amount of time the blood takes to form a clot. CLIA waved test. Blue top tube

Answer 1

Prothrombin time (PT)

Question 2

Critical element in production of prothrombin time

Answer 2

Vitamin K

Question 3

Rate at which RBCs settle out of anticoagulant blood specimen after 30 minutes (mm/hr)

Answer 3

ESR- erythrocyte sedimentation rate

Question 4

Abnormal condition of increased # of RBC

Answer 4

Polycythemia

Question 5

Sickle shaped, caused by inherited Hgb-S molecule

Answer 5

Sickle cell

Question 6

All blood elements show decrease, inability to produce cells in bone marrow

Answer 6

Aplastic

Question 7

Deficient in vitamin B12/intrinsic factor is lacking cells appear enlarged and fragile

Answer 7

Pernicious

Question 8

Increase in reticulocytes in peripheral blood due to RBC destruction caused by inherited thalassemia

Answer 8

Thalassemia and hemolytic

Question 9

Most common type of anemia, inability to build healthy hgb caused by blood loss/inadequate iron in diet

Answer 9

Iron deficiency

Question 10

Abnormal increase in # of WBC

Answer 10

Leukocytosis

Question 11

Low WBC count, abnormal ( sign of aplastic anemia, HIV, chemo)

Answer 11

Leukocytopenia

Question 12

Atypical reactive lymphocytes

Answer 12

Mononucleosis

Question 13

Abnormal decrease in # of WBC

Answer 13

Leukopenia

Question 14

Various cancers of WBCs

Answer 14

Leukemia

Question 15

ALL

Answer 15

Acute lymphocytic leukemia (sudden onset)

Question 16

CML

Answer 16

Chronic myeloid leukemia (ongoing)

Affects lymphoblasts

Question 17

Microhemarocrit lab procedure

Answer 17

2 capillary tubes
Counter balance and centrifuge for 5 minutes
Capillary results should be within 2% of eachother

Question 18

Hematocrit tubes

Answer 18

Contain heparin

Question 19

Spun hematocrit tubes

Answer 19

Yellow-plasma
Buffy coat (WBC & platelets)
Orange- RBC
Bottom-clay/seal

Question 20

CBCs

Answer 20

Consist of 7 lab tests

Question 21

Cou noted and reported in millions per cubic millimeters million/mm3

Answer 21

RBC total count

Question 22

% of packed RBC

Answer 22

Hematocrit- HCT

Question 23

amount of hemoglobin released released after RBCs have been hydrolyzed. RBC is measured

Answer 23

Hemoglobin- Hgb

Question 24

RBC indices- what are they used to diagnose and ratio elements

Answer 24

Causes of anemia and polycythemia

Question 25

Mean (average) cell hemoglobin concentration hgb/Hct

Answer 25

MCHC

Question 26

Mean cell hemoglobin hcb/rbc

Answer 26

MCH

Question 27

Hct/rbc

Answer 27

MCV

Question 28

Thousands per cubic millimeter

Answer 28

WBC total count

Question 29

% of each type compared to reference values 5 WBC/ leuekocytes

Answer 29

Differential count

Question 30

Approximation on stained slide or by automated instrument

Expressed in hundreds of thousands per cubic millimeters

Answer 30

Platelets

Question 31

Normal reference range for hemoglobin

Answer 31

Men: 14-18g/do
Female: 12-16 g/dL

Question 32

Normal reference range for ProTime/INR

Answer 32

12-18 seconds PT

2-2.5 INR

Question 33

Normal reference range for ESR

Answer 33

0-20 mm/hr

Question 34

Normal reference range for hematocrit

Answer 34

Men: 42-52%
Female: 36-45%

Question 35

Screening tests for PT

Answer 35

Patient lacks clotting factor
Liver disease
Vitamin k deficiency