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Clinical Med I > MSK/Rheumatology - RA, OA - Exam 3 > Flashcards

MSK/Rheumatology - RA, OA - Exam 3 Flashcards

1
Q

External trigger (ex: smoking) > Autoimmune + Inflammatory response > synovial hypertrophi + joint inflammation > Destruction of joints > Joint deformity is the progression of what disease?

A

Rheumatoid arthritis

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2
Q

What inflammatory disease is characterized by symmetrical polyarthritis that progresses from periphery to proximal and has improvement with movement?

A

Rheumatoid arthritis

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3
Q

How can Rheumatoid arthritis present in the hand?

A

Affects MCP and PIP joints
Spares DIP joints
Swan neck and boutonniere deformaties
Ulnar deviation

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4
Q

How can Rheumatoid arthritis present in the upper extremities?

A

Carpal tunnel
Frozen shoulder
Rheumatoid nodules

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5
Q

How can Rheumatoid arthritis present in the lower extremities?

A

Affects MTP joints on the feet

Popliteal (bakers cyst)

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6
Q

What part of the axial skeleton can rheumatoid arthritis affect t?

A

Cervical spine C1-C2

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7
Q

How does rheumatoid arthritis affect the cervical spine?

A

Cerval subluxation

Cervical myelopathy

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8
Q

What is seen in the lab results of person with rheumatoid arthritis?

A

Rheumatoid factor (RF)
ant-CCP antibodies
ANA ~30% of patients

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9
Q

What pharmacological agent is given to all patients dx with rheumatoid arthritis?

A

DMARDs

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10
Q

How long does morning stiffness last with rheumatoid arthritis?

A

More than 1 hr

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11
Q

What are the characteristics of the joints with rheumatoid arthritis?

A

Soft, warm, tender

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12
Q

Does RA or OA have more extraarticular manifestations?

A

RA

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13
Q

What degenerative disease is characterized by joint pain stiffness and functional impairment of all joint tissues and has improvement with rest?

A

Oesteoarthritis

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14
Q

How can osteoarthritis present in the hand?

A

Affects the MCP, PIP, and DIP joints
Heberden’s nodes
Bouchard’s nodes

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15
Q

How can osteoarthritis present in the lower extremities?

A

Most common in knees and hip
Swelling
Restricted ROM

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16
Q

How long does morning stiffness last with osteoarthritis?

A

Less than 30min

17
Q

What are the characteristics of the joints with osteoarthritis?

A

Hard and bony

18
Q

How is osteoarthritis diagnosed?

A

Clinical
Weight baring imaging
No definitive lab tests

19
Q

How is rheumatoid arthristis diagnosed?

A

ACR/EULAR criteria

1 joint with definitive clinical synovitis

20
Q

What is the treatment for osteoarthritis?

A

Treat pain and inflammation

Surgery if conservative tx fails

21
Q

What inflammatory disease is characterized by proximal aching and stiffness associated
with giant cell temporal arteritis?

A

Polymyalgia Rheumatica

22
Q

How long does morning stiffness last with polymyalgia rheumatica?

A

More than 1 hr

23
Q

Symptoms of PMR are due to what?

A

Synovitis, tenosynovitis, and bursitis

24
Q

Where are the most common locations of pain with polymyalgia rheumatica?

A

Shoulder and pelvic girdle

Difficulty brushing hair or rising from a chair

25
Q

How does polymyalgia rheumatica affect the shoulders?

A

Restricted ROM
Pain
Normal muscle strength

26
Q

How is polymyalgia rheumatica diagnosed?

A

No established criteria
Elevated ESR
Rapid resolution with glucocorticoids

27
Q

What inflammatory disease is characterized by widespread pain lasting for more than 3 months, extreme fatigue, cognitive disturbances with an absence of joint swelling/inflammation?

A

Fibromyalgia

28
Q

What are the nonpharmacological treatment option for Fibromyalgia?

A

Exercise
PT
Cognitive behavioral therapy

29
Q

What are the pharmacological treatment options for Fibromyalgia?

A

Tricyclic antidepressant
SNRIs- Duloxetine, Milnacipran
Anticonvulsants- Pregabalin, Gabapentin

Clinical Med I (24 decks)

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