Lecture 1 Key Terms Flashcards

1
Q

What makes lesions white?

A
  1. Thicker Surface (more keratinized tissue on epithelial surface)
  2. Thicker Epithelium (increase thickness of the prickle layer)
  3. Edematous cells

examples include pseudomembranous candidiasis (wipeable), leukoedema, leukoplakias with dysplastic changes, or lichen planus

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2
Q

What makes a lesion red?

A
  1. Thin epithelium (epithelial atrophy)

2. Increase in the submucosal blood vessels (hemangioma)

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3
Q

Features of an intra-oral soft tissue lesion

A
  1. Color
  2. Relationship to surrounding mucosa
  3. Number/Pattern/Location/Distribution
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4
Q

What is an oral ulcer?

A

Look for surface topography: may be subtle b/c ulcers can be superficial
Ulcers (especially chronic ulcers) are typically tan in color because of the fibrin pseudomembrane

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5
Q

Define: Papule

A

solid elevated lesion measuring <5 mm diameter

ex. Lymphoepithelial cyst

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6
Q

Define: Nodule

A

solid elevated lesion measuring >5mm but <2cms diameter

ex. Irritation fibroma

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7
Q

Define: Tumor

A

solid elevated lesion measuring >2cm diameter

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8
Q

Define: Plaque

A

solid elevated lesion measuring >5mm diameter and is almost flat

ex. Leukoplakia

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9
Q

Define: Vesicle

A

fluid filled elevated lesion measuring <5mm diameter

ex. Herpes Labialis

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10
Q

Define: Bulla

A

fluid filled elevated lesion measuring >5mm diameter

ex. MMP

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11
Q

Define: Pustule

A

fluid filled elevated lesion measuring 5mm diameter and contains pus

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12
Q

Annular

A

ring-like

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13
Q

Atrophic

A

reduction in thickness

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14
Q

Bosselated

A

covered with small bosses (protuberances) on the surface

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15
Q

Corrugated

A

like folded construction paper (think of a SUN-CHIP)

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16
Q

Crusted

A

dried and flaky

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17
Q

Desquamative

A

sloughing of the epithelium

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18
Q

Edematous

A

swollen

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19
Q

Erosive

A

partial loss of epithelium

20
Q

Erythematous

A

red

21
Q

Fissured

A

grooved

22
Q

Fluctuant

A

In regards to palpation, feeling like it is filled with pus

23
Q

Fixed

A

In regards to palpation, difficult to move; feels stuck to something. THINK LYMPH NODES

24
Q

Granular

A

rough/grainy

25
Q

Hairy

A

hair-like projections

26
Q

Homogenous

A

same color throughout lesion

27
Q

Indurated

A

In regards to palpation, feels firm or hard

28
Q

Macerated

A

frayed appearance

29
Q

Melanotic

A

dark brown/black pigmentation

30
Q

Necrotic

A

implies dead tissue

31
Q

Papillary

A

finger-like projections

32
Q

Pebbled

A

bumpy

33
Q

Pedunculated

A

has a stalk

34
Q

Punctate

A

point-like

35
Q

Reticular

A

lacy or net-like

36
Q

Serpiginous

A

wavy or snake-like

37
Q

Sessile

A

attached by wide base

38
Q

Speckled

A

mixed color/red&white

39
Q

Spongy

A

compressible

40
Q

Telangectatic

A

vascular dilatations

41
Q

Verrucous

A

wart-like

42
Q

Sensitivity

A

(also called the true positive rate) measures the proportion of positives that are correctly identified as such (eg the percentage of people
with oral cancer/precancer who are correctly identified by the test as having
these diseases)

True Positive results (TP) divided by true positive plus false negative results (FN)

TP/(TP+FN)

43
Q

Specificity

A

(also called the true negative rate) measures the proportion of negatives that are correctly identified as such (e.g., the percentage of healthy
people who are correctly identified as not having these diseases)

True Negative results (TN) divided by true negative plus false positive results (FP)

TN/(TN+FP)

44
Q

Light based adjuncts sensitivity results

A

Sensitivity 0.90

Meaning…the test rendered a positive result for 90% of
those who were diagnosed by histopathology (gold standard) to have the disease (ie any grade of dysplasia or squamous cell carcinoma).

False negative rate was 10% meaning the light-based adjunct is negative yet the histopathology is positive and you just told your patient they’re fine when they actually have disease

45
Q

Light based adjuncts specificity results

A

Specificity = 0.52

Meaning… the test rendered a negative result for 52% of those who were diagnosed by histopathology (gold standard) to not have the disease (ie neither dysplasia nor squamous cell carcinoma).

The False Positive rate was 48% meaning that that you tell the patient the test was positive but in reality they don’t have the disease