Goodpasture's syndrome Flashcards

1
Q

What is it?

A

anti-GBM abs against type IV collagen

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2
Q

How does it present?

A

pulmonary haemorrhage

rapidly progressive glomerulonephritis

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3
Q

What factors increase likelihood of pulmonary haemorrhage?

A

smoking
LRTI
Pulmonary oedema
Young male

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4
Q

wHat are the investigations?

A

reanl biopsy - linear IgG deposits along BM

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5
Q

What is the management?

A

plasma exchange
steroids
cyclophosphamide

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