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pom week 1 > Glycolysis > Flashcards

Glycolysis Flashcards

1
Q

3 steps of Cellular Metabolism

A

Glycolysis
TCA/Krebs Cycle
Oxidative Phosphorylation

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2
Q

6 types of metabolic reactions

A 
Oxidation-Reduction
Ligation requiring ATP cleavage 
Isomerisation
Group Transfer
Hydrolytic 
Addition/Removal of functional groups
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3
Q

3 facts about glycolysis

A

Central to metabolism
Anaerobic process
Occurs in Cytosol

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4
Q

Overall reaction for Glycolysis

A

Glucose + 2ADP + 2Pi + 2NAD+ ——-> 2Pyruvate + 2ATP + 2NADH + 2H+

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5
Q

2 main concepts of glycolysis

A

Invest energy in the form of ATP to form a high energy compound
Produces energy in the form of ATP by splitting a high energy compound

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6
Q

Step 1 of glycolysis

A

Irreversible group transfer
Catalysed by hexokinase
Consumes 1ATP
Forms Glucose-6-Phosphate

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7
Q

Step 2 of glycolysis

A

Isomerisation
Catalysed by phophoglucose isomerase
Forms fructose-6-phosphate

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8
Q

Step 3 of glycolysis

A

Group transfer
Catalysed by phosphofructokinase
Consumes 1ATP
Forms symmetrical fructose-1,6-biphosphate

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9
Q

Step 4 of glycolysis

A

Hydrolytic reaction
Catalysed by aldolase
Gives glyceraldehyde-3-phosphate and dihyroxyacetone phosphate

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10
Q

Step 5 of glycolysis

A

Isomerisation
Catalysed by triose phosphate isomerase
Gives glyceraldehyde-3-phosphate

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11
Q

Step 6 of glycolysis

A

Redox and Group Transfer
Catalysed by glyceraldehyde 3-phosphate dehydrogenase
NAD+ reduced generating NADH
Forms 1,3 biphosphoglycerate

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12
Q

Step 7 of glycolysis

A

Group transfer
Catalysed by phosphoglycerate kinase
Generates 1ATP
Forms 3-phosphoglycerate

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13
Q

Step 8 of glycolysis

A

Isomerisation
Catalysed by phosphoglycerate mutase
Forms 2-phosphoglycerate

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14
Q

Step 9 of glycolysis

A

Group removal (dehydration)
Catalysed by enolase
Forms phosphoenolpyruvate

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15
Q

Step 10 of glycolysis

A

Group transfer
Catalysed by pyruvate kinase
Yields ATP
Forms Pyruvate!

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pom week 1 (9 decks)

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