Midterm 1 - Neuroanatomy, Blood Supply, MCDB, CNS, PNS, CNs Flashcards

1
Q

Sectioning the Brain

(Image)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Directions and the Brain

A

Top of Brain - Dorsal (also the back)

Bottom of Brain - Ventral (also the belly)

Front - Rostral (anterior)

Back - Caudal (posterior)

Lateral - Towards side

Medial - Towards middle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Planes of the Brain

(Image)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lobes of the Brain

(Image)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sulcus vs. Fissure vs. Gyrus

A

Brain is gyrencephalic.

Sulcus

  • Groove

Fissure

  • Deep groove

Gyrus

  • Bump
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Ventricles

(Image)

A
  • Lateral (2)
  • 3rd
  • 4th
    • Cerebral Acqueduct
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Corpus Callosum

A
  • Thick bundle of axons that facilitates the transmission of information from one hemisphere to the other.
  • Connects like areas of brain.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CSF

A
  • Fills ventricles
  • Made by choroid plexus of each ventricle. The CP of each ventricle gets a blood supply and takes what it wants to make CSF (clear part of blood).
  • Drains to 4th ventricle where it becomes a part of the blood supply again.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Meninges in the CNS

A
  • Protective sheaths around brain and spinal cord.
  • Pia Mater - thin, delicate layer on top of brain
  • Arachnoid Layer - Hollow space where the blood vessels supply the brain with blood
  • Dura Mater (outermost) - Beneath skull; thick, tough
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Meninges in the PNS

A

No arachnoid layer, just dura and pia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does blood carry to the brain?

A
  • Glucose
  • Oxygen

Brain is only 2% of body’s weight but uses 20% of body’s oxygen and 20% of body’s glucose.

7 min w/o oxygen and neurons begin to die.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Arteries Going to Brain

A
  • Carotid (2) - come off front of heart, go up front of spinal cord, go to front of brain
  • Vertebral (2) - come off heart and go up spinal cord, supplying blood to the back 1/2 of the brain (go thru hole in bottom of skull: “foramen magnum”).
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Primary Vein Leaving Brain

A

Jugular (carries de-oxygenated blood away)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

2 Ways Blood Supply to Brain Is Interrupted

A
  1. Stroke/CVA - Plaque in large artery breaks free and gets stuck in smaller branch (in brain).
  2. Anneurism - Outpouching of artery. Bursts and blood doesn’t get to the neurons it needs to get to.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Blood-Brain Barrier

A

Comprised of tight junctions of epithelial cells that make up the walls of arteries in the brain. Actually the lining of the arteries themselves.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

MCDB

A

Molecular Cellular Developmental Biology

  • We start as a tube and develop from the inside out, forming 6 layers that become the brain.
  1. Proliferation of neural stem cells in SVZ
  2. Migrate to radial glia cells
  3. Differentiate as climb up radial glia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Encephalons

A

Tel, Di, Mes, Met, Myel: Become brain and spinal cord

  • Telencephalon - Forebrain; Lateral ventricles, cerebral cortex (F-POT), Basal Ganglia, Limbic; front part of brain; becomes brain proper
  • Diencephalon - Forebrain; 3rd ventricle, thalamus, hypothalamus
  • Mesecephalon - Midbrain, cerebral aqueduct, tectum, tegmentum
  • Metencephalon = Hindbrain; 4th ventricle; cerebellum, pons
  • Myelencephalon = Hindbrain, medulla
18
Q

Embryonic Brain Development

(Encephalons)

A
19
Q

Encephalons

(Image of Brain)

A
20
Q

Brainstem

A
  • Medulla (myelencephalon)
  • Pons (metencephalon)
  • Midbrain (mesencephalon)
21
Q

CNS

A
  • Brain + Spinal Cord
  • Encased in bone
22
Q

PNS

A
  • Cranial nerves (except for Optic II which is part of diencephalon tract)
  • Spinal Nerves
  • All nerves that come from your entire body

Somatic - Receives sensory info and controls movement of skeletal muscles

ANS

  • Sympathetic
  • Parasympathetic
23
Q

Cranial Nerves

(Overview Image)

A
24
Q

Cranial Nerves

(All 12)

A

O, O, O, Titty, Twat, Ass, Fuck, A, Girl’s, Vagina, Says, Hi

  1. Olfactory - Smell
  2. Optic - Vision
  3. Oculomotor - Eye movement
  4. Trochlear - Eye Movement
  5. Trigeminal - Jaw Movement
  6. Abducens - Eye Movement
  7. Facial - Face muscles
  8. Auditory - Hearing
  9. Glossopharyngeal - Muscles of throat and larynx
  10. Vagus - Internal Organs
  11. Spinal Accessory - Neck Muscles
  12. Hypoglossal
25
Q

Cranial Nerve

A

Nerve that emerges directly from brain.

Don’t go into spinal cord or thalamus.

26
Q

Brain

A

Cortex + Brain Stem

27
Q

Brain:

Gray Matter

v.

White Matter

A

Gray

  • Cell Bodies (outside)

White

  • Myelin (inside)
28
Q

Spinal Cord:

Gray Matter

v.

White Matter

A

White

  • Myelin (outside)

Gray

  • Cell bodies (inside)

Opposite of brain

29
Q

Afferent Axon

A

An axon directed toward the CNS, conveying sensory information

***Dorsal Root***

30
Q

Efferent Axon

A

An axon directed away from the CNS, conveying motor commands to muscles and glands

***Ventral Root***

31
Q

Law of Bell & Magendie

A

Segregation of Spinal Cord

  • Anything above the midline (dorsal portion of spinal cord) is info going to brain from the senses.
  • Anything below the midline (ventral portion of spinal cord) is info coming from the brain to the muscles.
32
Q

2 Types of Cells in CNS

A
  1. Neurons
  2. Glia
33
Q

Types of Glia Cells

A
  1. Oligodendrocytes
  2. Schwan Cells
  3. Microglia
  4. Macroglia
  5. Astrocyte
34
Q

Oligodendrocyte

A
  • CNS
  • Big
  • Provide myelin
35
Q

Schwan Cell

A
  • PNS
  • Smaller than oligo
  • Provide myelin
36
Q

Substantia Gelatinosa

A
  • Junction of oligos & schwan
  • Entry to CNS (bacteria can get in)
  • Where PNS goes into spinal cord
37
Q

Microglia + Macroglia

A

Both involved in immune system in brain.

Eat things

38
Q

Astrocytes

A
  • Starts of the nervous system
  • Support neural transmission
  • Store glucose (takes from arteries)
  • Store ions
  • Maintain balance of NTs at synpse by sucking up extra NT or supplying NT when there’s not enough
39
Q

Glia Cells

v.

Neurons

A

Glia Cells

  • Can proliferate out of control and form tumors (“glyomas”)
  • Can mutate

Neurons

  • Don’t divide
  • Once differentiated, stay a particular type of cell
  • Never form tumors
40
Q

Time Frame for Neuron Proliferation, Migration and Differentiation

A
  • Start in 2nd trimester and continues thru 2 yrs old
  • Neurons steadily die after age 2 and perhaps reach peak neuronal density before born
41
Q

Synaptic Plasticity

A

Brain can change.

A neuron’s ability to form new synapses with other neurons.

How you learn (a physical structure is created every time you learn)

42
Q

3 Things Affecting Brain Health

A
  1. Exercise
  2. Nutrition
  3. Sleep