Exam 3 - Meds

Question 1

Describe Albuterol’s MOA

Answer 1

In the lungs: Sympathetic → Epinephrine → (adrenergic receptors - ß2) → BRONCODILATION

Albuterol is a ß2-Adrenergic agonist, so cells get more epinephrine and bronchials dilate

Question 2

What are the side effects of Albuterol?

Answer 2

Nervousness, shaking, palpitation, HYPOKALEMIA, HYPERGLYCEMIA

(Stimulates epinephrine- activates glycogenolysis, K+ being pumped out of cell, increased HR)

Question 3

What is the drug of choice for respiratory disorders?

Answer 3

Albuterol

Question 4

Describe Olanzapine. What is it used for?
What is it’s MOA?
Side Effects?

Answer 4

Anti-psychotic

MOA: serotonin, dopamine, muscarinic receptor antagonist (attempting to rebalance neurotransmitters)

SE: WEIGHT GAIN, constipation, hyperlipidemia, hyperglycemia

Question 5

When should weight loss drugs be started? When should it be discontinued?

Answer 5

Started:
• BMI >/= 30
•BMI >/= 27 w/other issues like high BP, high cholesterol, or T2DM

Stopped:
• Fails to lose sufficient (5-10%) amounts of body weight after 3 months
•Experience significant adverse events

Question 6

Describe Lisinopril. What is it used for?
What is it’s MOA?
Side Effects?

Answer 6

Angiotensin Converting Inhibitor (ACEI)

MOA: blocks ACE, inhibiting conversion of angiotensin I to angiotensin II (which is a potent vasoconstrictor). This lowers aldosterone (so low Na/H2O reabsorption and more K reabsorption)

SE:
• Dry cough
• Hypotension
• Hyperkalemia

Question 7

What kind of drugs end with -LOL? Describe

Answer 7

Beta blockers

MOA: decrease cardiac output and inhibit rening

SE: dry mouth, bradycardia, hypotension, fatigue, hyperglycemia, hypertriglyceridemia, depression