Adipose Tissue

Question 1

What chemicals does adipose release?

Answer 1

Leptin
CRP
TNF alpha
IL-6
Oestrogen 
Cortisol
Free fatty acids

Question 2

What is the function of leptin in the body?

Answer 2

Tracks and monitors bodies adipose levels

Question 3

If there are low levels of leptin what does this trigger?

Answer 3

Increased appetite

Decreased thermogenesis

Question 4

If there are high levels of leptin what does this trigger?

Answer 4

Decreased appetite

Increased thermogenesis

Question 5

What is the only drug licensed for weight loss?

Answer 5

Orlistat

Question 6

What is the mode of action of orlistat?

Answer 6

Lipase inhibitor

Blocks dietary absorption of fat

Question 7

What are some side affects of Orlistat?

Answer 7

GI diarrhoea

Steatorrhea

Question 8

What are the three forms of bariatric surgery

Answer 8

Adjustable gastric band
Roux-en-Y gastric bypass
Vertical sleeve gastrectomy

Question 9

What are the pros and cons of a gastric band?

Answer 9

Least invasive

However if there is dramatic weight loss the band can slip superiorly and inhibit any food intake

Question 10

At what weight can you be considered for bariatric surgery?

Answer 10

BMI 40

BMI 35 with significant related health issues e.g. diabetes