STI's Flashcards

1
Q

Chlamydia organism

A

Chlamydia trachomatis

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2
Q

Diagnosis of chlamydia

A

NAAT - nucleic acid amplification test
First pass urine in men
Vulvovaginal swabs in women

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3
Q

When is the ideal time to carry out chlamydia testing

A

2 weeks after a possible exposure

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4
Q

Microscopy showing red inclusion bodies are typical of which infection

A

Chlamydia

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5
Q

Management of chlamydia

A

Azithromycin 1g single oral dose OR
Doxycycline 100mg PO BD for 7 days OR
Erythromycin 500mg PO BD for 14 days

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6
Q

What is Fitz-Hugh-Curtis syndrome

A

A rare complication of pelvic inflammatory disease (PID) involving liver capsule inflammation leading to the creation of adhesions.

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7
Q

What is lymphogranuloma venereum and what are the symptoms of it

A

An infection caused by a more invasive serotype of chlamydia trachomatis which causes a triad of inguinal lymphadenopathy, proctocolitis and fever

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8
Q

In England what ages is the national chlamydia screening programme open to

A

Age 15-24

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9
Q

Organism that causes gonorrhea

A

Neisseria gonorrhoeae (gram negative diplococci)

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10
Q

Diagnosis of gonorrhea

A

NAAT - nucleic acid amplification test
First pass urine in men
Vulvovaginal swabs in women
Urethral/cervical/anal/oral swabs taken for culture prior to administering antibiotics to assess sensitivities

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11
Q

Management of gonorrhea

A

Ceftriaxone 500mg IM injection single dose AND Azithromycin 1g oral single dose

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12
Q

How long after gonorrhea treatment do you test again as a test of cure

A

2 weeks

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13
Q

Organism that causes syphilis

A

Treponema pallidum

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14
Q

What are the 5 stages of syphilis

A
Primary
Secondary
Early latent
Late latent
Tertiary
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15
Q

What is the primary stage of syphilis infection characterised by

A

Development of an indurated painless ulcer called a chancre most often on the genitals

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16
Q

What is the secondary stage of syphilis infection characterised by

A

6 weeks to 6 months following the primary infection a widespread non-pruritic maculopapular rash involving the trunk, palms and soles develops accompanied by alopecia, condylomata lata (painless, warty lesions on the genitalia), generalised lymphadenopathy, oral snail-track lesions and constitutional symptoms (pyrexia, fatigue, malaise).

17
Q

Features of tertiary syphilis

A

Neurosyphilis – Tabes dorsalis (dorsal column demyelination), general paresis, strokes, Argyll-Robertson pupil (bilaterally small pupils that accommodate but don’t constrict directly to light)
Cardiovascular syphilis – Aortitis, aortic aneurysms
Gummatous syphilis – Formation of granulomas on bone, skin and mucosa

18
Q

Features of congenital syphilis

A

Blunted upper incisor teeth (Hutchinson’s teeth)
Rhagades (linear scars at the angle of the mouth)
Saber shins (anterior bowing of the tibia)
Saddle nose
Deafness
Keratitis

19
Q

Management of syphilis

A

Benzathine benzylpenicillin 1.8g IM single dose AND Prednisolone 60mg PO OD for 3 days (give for 24hrs before the IM injection)

20
Q

Which herpes virus is spread via the oral route

A

HSV 1

21
Q

Which herpes virus is spread via the genital route

A

HSV 2

22
Q

Diagnosis of herpes

A

HSV PCR or culture from swabs taken from lesions- when taking the sample remember to burst the lesion and swab the fluid/base of the ulcer.

23
Q

Management for the primary episode of genital herpes

A

Aciclovir 400mg PO TDS for 7-10 days

24
Q

Management for recurrent episodes of genital herpes

A

Aciclovir 800mg PO TDS for 2 days

25
Q

Ideally, within how many days from symptom onset should you give Aciclovir in the primary episode of genital herpes infection

A

Within 3 days

26
Q

Which viruses cause genital warts

A

HPV 6 and 11

27
Q

First line management of genital warts

A

Topical podophyllotoxin

Topical imiquimod

28
Q

Second line management of genital warts

A

Cryotherapy

Surgical excision

29
Q

Type of vaginal discharge caused by TV

A

Thin, frothy
Yellow-green
Fishy smell

30
Q

Diagnosis of TV

A

Alkaline vaginal pH
High vaginal swab for microscopy, culture of discharge
In men - urethral swab or first pass urine

31
Q

Treatment for TV infection

A

Metronidazole 2g oral as single dose