acne Flashcards
commonly affected areas
face back and chest
what is a blocked follicle called
comedogenesis
pathogenesis of acne
increased or altered production of sebum
growth of cutibacterium acnes, with sebum in hair follicles
this stimulates inflammation and production of fatty acids
keratinocyte proliferation also blocks follicle causing further inflammation
risk factors
genetics, hi gi foods, medications, pcos, stress, smoking, cosmetics
mild acne symptoms and size of lesions
papules and pustules <5mm di
moderate acne symptoms and size of lesions
nodules and cysts >5mm
what is considered severe acne
scarring, large affected area and treatment failure
mild - mod treatment
BPO usually with retinoid
topical retinoid- adapaline
azelic acid - reduce irritation
topical antibiotic - clindamycin usually with BPO
moderate treatment
oral antibiotic (doxycycline) with topical retinoid can add BPO
which acne medications should be avoided during pregnancy
topical retinoid and oral antibiotics
which acne medications require sun protection
BPO, retinoid and oral antibiotics
advice
use non-comedogenic products
apply products to whole affected area
do not over clean skin
no not pick lesions - scar
severe treatment and moa
isotretinoin
reduces sebum secretion by causing apoptosis to sebocytes
decreases hyperkeratinisaton
anti inflammatory properties
risks of isotretinoin
teratogenic, depression and anxiety
impaired night vision
dry and fragile skin = uv protection
