Antidepressiva Flashcards

1
Q

Amitriptylin, Doxepin

A

NSMR I = nicht-selektive Monoamin Reuptakeinhib, cave

CYP2D6 + anticholnerg+ sedierend+ gewichtzunahme+alpha1 Antidepressiva

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2
Q

Fluoxetin, Paroxetin

A

ältere SSRI = selektive Serotonin Reuptakeinhibitoren,

CYP2D6-inhibitoren ! Antidepressiva uaw QT! blutungsneigung G.I: hyponatremie

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3
Q

Citalopram, Sertralin

A

neuere SSRIs, hochselektiv, weniger Interaktionen Antidepressiva

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4
Q

Venlafaxin

A

SSNRI = selektiver Serotonin- u. Noradrenalin-

Reuptakeinhibitor uaw Mehr durchfall Antidepressiva

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5
Q

Mirtazapin

A

α2-Antagonist, zusätzlich H1, 5-HT2, 5-HT3; Müdigkeit,

Gewichtszunahme Antidepressiva

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6
Q

Moclobemid

A

MAO-A Hemmer, reversibel, antriebssteigernd Antidepressiva

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7
Q

Tranylcypromin

A

unselektiver MAO-Hemmer, irreversibel, cave Tyramin Antidepressiva

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8
Q

Johanniskraut

A

leichte/milde Depression, wirksam?, Induktion CYP3A4, gp-

170 Antidepressiva

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