Hyperlipidaemia Flashcards
What are risk factors for hyperlipidaemia?
Smoking
Hypertension
Diabetes
FH
What is familial hyperlipidaemia?
Genetic hyperlipidaemia (same as primary)
Raised LDL
What is primary hyperlipidaemia?
Genetic hyperlipidaemia (same as familial)
Raised LDL
What is there an increased risk of with primary/familial hyperlipidaemia?
CHD
What is secondary hyperlipidaemia?
High lipids as a result of
- diabetes
- alcohol abuse
- low T4
- renal failure
How is hyperlipidaemia managed?
Lifestyle changes
Statins = first line
Second line
- fibrates
- cholesterol absorption inhibitors
What is the QRISK2 score?
Cardiovascular disease risk calculator
What is significant about QRISK2?
Anyone with a score over 10% should be on a statin
How soon should lipid profile be repeated after starting a statin?
3 months
What are side effects of statins?
Myopathy
Liver impairment
When should LFTs be checked with a statin?
At start
3 months
12 months
When should you stop statins?
Macrolide antibiotic
Pregnancy
