Stomach Flashcards

1
Q

What initiates the swallowing reflex? Is it under voluntary or involuntary control?

A

The swallowing centre in the medulla

Involuntary

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2
Q

What causes botulism - inability to swallow?

A

Clostridial toxins block acetylcholine release

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3
Q

What is impaired by anaesthesia?

A

The swallowing reflex

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4
Q

What type of epithelium makes up the mucosal layer of the oesophagus?

A

Stratified squamous epithelium

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5
Q

How is the muscle layer of the oesophagus composed?

A

Inner circular muscle and outer longitudinal muscle

composed of smooth and striated muscle

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6
Q

What opens at the bottom of the oesophagus to allow food into the stomach?

A

lower oesophageal sphincter

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7
Q

Which animal cannot self regurgitate?

A

Horse

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8
Q

Describe the process of vomiting

A
  • deep inspiration with simultaneous closure of trachea
  • forceful contraction of abdominal muscles
  • cardiac sphincter opens
  • food propelled up oesophagus
  • upper oesophageal sphincter opens
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9
Q

What can be caused due to gastric torsion (stomach rotation)?

A
  • seals off cardiac sphincter preventing vomiting
  • compromised blood supply causing gastric tissue to become oedematous/hypoxic
  • can impair venous return to the heart causing circulatory shock
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10
Q

What is chyme?

A

Broken down food that has been mixed with gastric juice

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11
Q

Which chamber is the ruminant equivalent of a simple stomach?

A

Abomasum

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12
Q

What are the 4 regions of the stomach?

A

Cardia
Fundus
Corpus
Pylorus

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13
Q

What is secreted by

1) parietal cells
2) chief cells

A
1 = HCl to digest protein
2 = pepsinogen to digest protein
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14
Q

What is receptive relaxation?

A

When an animal starts eating there is an initial relaxation of stomach smooth muscle to accommodate the meal

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15
Q

What stimulates the emptying of the stomach?

A
  • expansion of stomach walls increases the strength of contraction
  • release of gastrin
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16
Q

What digests starch and at what pH?

A

Amylase at a pH greater than 6

17
Q

What digests protein and at what pH?

A

Pepsin at a low pH

18
Q

Describe the structure of starch

A
  • complex carbohydrate
  • mixture of amylose and amylopectin
  • linked by 1-4 α-glycosidic bonds
19
Q

How is starch broken down before reaching the low pH stomach?

A

Salivary amylase in the mouth
Newly swallowed food enters the centre of the stomach so there is a delay between stomach acid being secreted from the stomach walls and it reaching the bolus

20
Q

Compare the levels of starch in the diets of carnivores, herbivores and omnivores

A
1 = low levels 
2 = low levels
3 = high levels
21
Q

compare salivary amylase levels in pigs, horses, carnivores and ruminants

A

Pigs = high
Horses = low
Carnivores and ruminants = absent

22
Q

Whats are the 2 primary components of gastric juice?

A

HCl and pepsinogen

23
Q

What is the alkaline tide?

A

Urine pH increases just after a meal due to a delay between food passing from the stomach to pancreas, caused by an increase in bicarbonate in the ISF

24
Q

Which 3 substances are the hormonal control of the GI system?

A

Acetylcholine, histamine and Gastrin (indirect)

25
Q

What is the cephalic phase of digestion?

A
- Neural stimulation
before food has entered stomach
Caused by sight, smell, taste, presence of food in mouth
Stimulates secretion@
- Directly via acetylcholine
- Indirectly via gastrin in blood
26
Q

What are the 3 phases of digestion?

A

Cephalic
Gastric
Intestinal

27
Q

How is the stomach mucosa protected from HCl?

A
  • secretion of mucous layer
  • Epithelial cell membrane and interconnecting tight junctions impenetrable by H+
  • Epithelial cells replaced every 2-3 days