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Oncology lecture B > Peads oncology presentation > Flashcards

Peads oncology presentation Flashcards

1
Q

Most common paediatric malignancies?

A

leukaemia’s
CNS
lymphoma
soft tissue sarcoma

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2
Q

When does a wills tumor present?

A

<1 yo

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3
Q

what brain malignancy present specifically in <3 yo?

A

ependymoma

choroid plexus Ca

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4
Q

What brain malignancy covers age groups 0-22?

A

medulla plastoma
Astrocytoma
cerebellar astro.

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5
Q

What dd for head back cancer?

A

NB
RMS
lymphoma

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6
Q

What predisposition syndrome cause cancer in kids?

A 
Retinoblastoma 
Li-fraumeni 
NF 1/2
AT
FA
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7
Q

What dx for horners syndrome?

A

NB

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8
Q

What dx for SVC obstruction

A

NHL

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9
Q

What dx for proptosis?

A

NB and RMS

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10
Q

What dx fora pathological fracture?

A

Osteosarcoma

Ewigs sarcoma

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11
Q

What dx for rashes

A

Hodkins

LCH - langerhans cell histiocytosis

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12
Q

What dx for night sweats?

A

lymphomas

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13
Q

What paediatric tumours cause hepatomegaly?

A

leukaemia
NB
Hepatoblastoma
mets

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14
Q

What paediatric tumours cause splenomegaly?

A

leukaemia

MDS

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15
Q

Rule of thumb… which signifies cancer, speno- or hepatospenomegaly?

A

Splenomegaly indicates tumour

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16
Q

What peadiatric tumours cause pelvic tumour

A

Rhabdos
Ovarian - teratoma, GC
sacrococcygeal teratomas

17
Q

What Sx of infra-tectorial tumours?

A 
CN palsies = brainstem 
CN VI (flash localising, failure = brainstemm)
Ataxia and co-ordination
18
Q

What Sx of supra-tectorial tumours?

A 
Raised ICP 
seizure 
UMN signs 
visual field defects 
diencephalic syndrome (hypothalamus)
19
Q

Ddx x-ray limb.

A

Osteomsarcoma
Ewings
Langerhan’s cell histiocytosis

20
Q

Spot diagnosis: punched out lesions in skull?

A

Langerhan’s cell histiocytosis

21
Q

Investigations of bone marrow aspirate shows dx of…

A

NB
RMS
lymphoma

22
Q

Investigations of LP aspirate shows dx of…

A

lymphoma

some bone tumours

23
Q

What can a MIBG scan help detect?

A

NB

24
Q

What can a urinary catecholamines help detect?

A

NB phaeos

25
Q

What are negative prognostic markers?

A

MCYN copy number
1p deletion
Gain of 17q

26
Q

What ChT affects lung function?

A

bleomycin

27
Q

Which tumours have a roll for ChT in delaying radiotherapy?

A

medulloblastoma
GCT
gliomas

28
Q

Why is asparaginase used in ALL?

A

depletes asparagine, which lymphoma cannot synthesis, therefore limiting growth.

29
Q

What function of age affects the prognosis of NB?

A

<1 yo - good survival

>2yo - poor survival

Oncology lecture B (4 decks)

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