Fluid shift across the capillary wall : pulmonary and systemic oedema Flashcards

1
Q

What fraction of body water us extracellular fluid?

A

1/3

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2
Q

How much of extra-cellular fluid is interstitial and what does interstitial mean?

A

75%

Bathing the body cells

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3
Q

What does interstitial fluid act as?

A

A go between for blood and body cells

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4
Q

The 4 components of the cardiovascular system?

A

Veins
Arteries
Capillaries
Arterioles

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5
Q

What do capillaries do?

A
  • Allow rapid exchange of gases, water and solutes with interstitial fluid
  • Deliver nutrients and O2 to body cells
  • Remove metabolites from cells
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6
Q

How many layers of endothelial cells on a capillary?

A

Single layer

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7
Q

What does blood flow into the capillary depend on?

A

Contractile state of the arterioles

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8
Q

What do terminal arterioles do?

A

Regulate regional blood flow to the capillary bed in most tissues

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9
Q

What do precapillary sphincters do?

A

Regulate blood flow in few tissues

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10
Q

Why is blood flow through the capillary bed slow?

A

To allow adequate time for exchange

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11
Q

What do capillaries unite to form?

A

Venules

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12
Q

How are exchangeable proteins moved across capillary wall?

A

Vesicular transport

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13
Q

What generally can’t cross capillary wall?

A

Plasma proteins and large molecules

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14
Q

What do lipid soluble substances go through in the capillary wall?

A

Endothelial cells of wall

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15
Q

What do water soluble substances go through in the capillary wall?

A

Water-filled pores

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16
Q

What is transcapillary fluid flow passively driven by?

A

Pressure gradients across capillary wall

17
Q

What is transcapillary fluid flow?

A

It is ultra-filtration

Exchange across the capillary wall of essentially protein free plasma