Libman-Sacks endocarditis Flashcards

1
Q

definition

A

autoimmune inflammation of heart valves that occurs as part of SLE

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2
Q

epidemiology

A

occurs in 50% of pts w/ lupus

usually occurs simultaneously w/ pericarditis

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3
Q

gross pathology

A

small to medium verrucous, berrylike, or flat vegetations
commonly on multiple valves
most commonly mitral and tricuspid, on either or both sides

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4
Q

microscopic pathology

A

necrotic debris
fibrinoid material
degenerating leukocytes, fibroblasts hematoxylin bodies

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5
Q

hematoxylin bodies

A

condensed naked nuclei of dead degenerated gells ingested by phagocytes

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6
Q

complications

A

chronic adhesive pericarditis

NOT emboli from the vegetations

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