Cancer Flashcards

1
Q

What is a tumour?

A

A mass forming lesion

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2
Q

What is neoplasm?

A

The autonomous growth of tissue beyond normal constraints of cell proliferation

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3
Q

What are benign and malignant tumours?

A

Bening - remain local

Malignant - Metastasize to other tissue

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4
Q

What type of tumour is cancer?

A

A malignant neoplasm

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5
Q

What are hamartomas?

A

Localised benign overgrowths of one or more mature cell types

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6
Q

What are heterotopias?

A

Normal tissue being found in parts of the body where they are not usually present

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7
Q

What are the suffixes for benign and malignant tumours?

A

Benign: -oma
Malignant: -sarcoma

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8
Q

What are teratomas?

A

Tumours derived from germ cells and can contain tissue derived from all 3 germ cell layers

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9
Q

What malignant tumours have the suffix ‘oma’?

A
  • Lymphoma
  • Melanoma
  • Hepatoma
  • Teratoma
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10
Q

What is direct extension of a tumour?

A

Stromal response to the tumour, includes:

  • Fibroblastic proliferation
  • Vascular proliferation
  • Immune response
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11
Q

What is haematogenous spread of a tumour?

A

Tumour metastasise through blood vessels

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12
Q

How do tumours spread through the lymphatics?

A

Cancer spreads through lymphatics to lymph nodes and beyond

Cancer spreads in the same pattern as the normal lymphatic drainage of the organ in question

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13
Q

What is translocoemic spread of cancer?

A

The cancer spreads through a body cavity, so can invade other organs in the same cavity

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14
Q

What is the perineural spread of cancer?

A

Spread via nerves as the cancer spreads along the nerve fibres

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15
Q

What is the TNM system of cancer description?

A

T- Tumour (the size and extent of local invasion)
N - Nodes (Number of lymph nodes involved)
M - Metasases (presence of cancer elsewhere in the body)

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16
Q

What do the grade and stage of cancer indicate about the tumour?

A

Grade - how differentiated the tumour is

Stage - How far has the tumour spread

17
Q

What is dysplasia?

A

An abnormal cell with an increased nuclear to cytoplasmic ratio