Antibiotic Guidelines

Question 1

Necrotising Fasciitis

Answer 1

Piperacillin / Tazobactam 4.5g IV
\+
Vancomycin 30mg/kg IV
\+
Clindamycin 600mg IV

Question 2

Meningitis Adults and children >2months

Answer 2

Ceftriaxone 2g (50mg/kg) IV
OR
Cefotaxime 2g (50mg/kg) IV
\+
Dexamethasone 10mg (0.15mg/kg) IV
\+
Vancomycin 30mg/kg IV (if Gram +ve cocci on LP)
\+
Benzylpenicillin 2.4g IV (if age > 50 or ETOH abuse)

Question 3

Encephalitis

Answer 3

Aciclovir 10mg/kg, (20mg/kg neonates) IV

Question 4

Meningitis < 2months

Answer 4

Cefotaxime 50mg/kg IV
+
Benzylpenicillin 60mg/kg IV

NO STEROIDS

Question 5

Ruptured Globe

Answer 5

Ceftazadime 2g (50mg/kg) IV
+
Vancomycin 20mg/kg IV

UpToDate

Question 6

Febrile Neutropenia

Answer 6

Piperacillin / Tazobactam 4.5g IV

Question 7

PID

Answer 7

Ceftriaxone 500mg IV or IM
\+
Azithromicin 1g + 1g PO 7 days later
\+
Metronidazole 400mg PO bd 14 days

Question 8

Empirical Treatment for sepsis - source not clear

Answer 8

Flucloxacillin 2g IV
+
Gentamicin 5-7mg/kg IV

Question 9

Native Valve Endocarditis

Answer 9

Flucloxacillin 2g q4hr IV
\+
Ampicillin 2g q4hr IV
\+
Gentamicin 1.5mg/kg q8hr

Dunn

Question 10

Bioprosthetic Valve Endocarditis

Answer 10

Vanc
\+
Gent
\+
Ceftriaxone to cover HACEK organisms