Aetiology Flashcards

1
Q

what is aetiology

A

the initiator of subsequent events resulting in patient illness

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2
Q

what is pathogenesis

A

mechanisms causing the disease

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3
Q

what is prognosis

A

outcome of a disease

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4
Q

what is epidemiology

A

the incidence, prevalence and population distribution of a disease

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5
Q

what is multifactorial aetiology

give examples

A

disease due to a COMBINATION of causes
eg diabetes is causedby genetic and env factors
diabetes is more env than genetic

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6
Q

what is unknown aetilogy known as

A

IDOPATHIC, PRIMARY, ESSENTIAL SPONTANEOUS, CRYPTOGENIC

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7
Q

what is a risk factor

A

the AETIOLOGY of a disease= unknown but the disease is OBSERVED with people with certain habit (eg smoking, age, occupationn)

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8
Q

what is pathogenesis

A

the MECHANISM through which AETIOLOGY operated to PRODUCE the PATHOLOGICAL AND CLINICAL MANIFESTATIONS

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9
Q

what is inflammation

A

a response to many microorganisms and other harmful agents, causing TISSUE INJURY

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10
Q

what is degeneration

A

a detrioration of cells/tissues in response to FAILURE OF ADAPTATION to a variety of agents

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11
Q

what is carcinogenesis

A

the MECHANISM by which canver-causing agents result in the development of tumours

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12
Q

what is a symptom of a disease

give common symptoms

A

what a patient SUFFERS, or COMPLAINS of

commonly: pain, fever, nausea

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13
Q

what are signs of a disease

give examples

A

what the doctor is looking for

eg body temp, bp

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14
Q

what is a syndrome

give an example

A

an AGGREGATE of SIGNS and SYMPTOMS or a combination of LESIONS without which the disease cannot be recognised/diagnosed
eg Cushing’s syndrome: caused by too much ACTH: obesity, hypertension, stretch marks on thigh, stomach, arms, legs, breasts, thinning skin that bruises easily

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15
Q

what is a lesion

give an example

A

the STRUCTURAL or FUNCTIONAL abnormality responsible for ill health
eg myocardial infarction (infarct/dead cardiac muscle= lesion)

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16
Q

what is a complication of a disease

give an example

A

prolonged, secondary or distant effects of a disease

eg lung embolism due to THROMBOSIS in the leg vein

17
Q

what is prognosis

A

the ANTICIPATED OUTCOME of disease

18
Q

what is the purpose of giving a prognosis

what is prognosis influenced by

A
  • to PLAN TREATMENT
  • GIVE INFO to patient
    influenced by: medical/surgical intervention
19
Q

what is the morbidity of a diease

A

the disease state of an individual or the INCIDENCE OF ILLNESS in a POPULATION , the PROPORTION OF PATIENTS with a PARTICULAR DISEASE DURING A given year PER given unit of population

20
Q

what is the mortality of a disease

A

probability that death with be the end result of that disease
- usually expressed as a % of all patients w/ disease

21
Q

what is the prevalence of a disease

how is it different to morbidity

A

the TOTAL no of cases of a given disease in a specified popuation at a designated time
morbidity= no of NEW CASES in the pop

22
Q

what are the 4 steps of disease
give examples of each stage for lung cancer
hypertension

A

aetiology–> pathogenesis–> disease–> complication

smoking–> genetic mutation–> lung tumour–> metastasis

many aetiologies–> inc renin production from kidneys–> high bp–> cerebral haemorrhage