Appetite Flashcards

1
Q

Although they play opposite roles, _______ and _______ are the two key appetite Hypothalamic Neuron Groups found within the Arcuate Nucleus.

A
  1. POMC/CART
  2. NPY (direct) & AgRP (indirect)
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2
Q

Name the double Arcuate Hypothalamic neuronal group responsible for increasing appetite.

A
  • NPY and AgRP

“Nippy and HANGRY”

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3
Q

NPY, MCH, AgRP, Orexin, and Endocannabinoids all ____ appetite

A

Increase

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4
Q

BMI is what two variables?

A

Weight/Height

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5
Q

Name the Arcuate Hypothalamic neuronal group responsible for Decreasing appetite.

A
  • POMC/CART; via a-MSH

“The cheerleaders use anorexic POM POMs”

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6
Q

PYY inhibits appetite by inhibiting which Arcuate neuronal Group?

A

NPY/AgRP

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7
Q

The Arcuate nucleus positively uses POMC/CART to make aMSH and negatively uses AgRP to respond to the ______ Receptor

A

MC4R

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8
Q

a-MSH, CART, GLP-1 ,and Serotonin all _____ appetite

A

Decrease

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9
Q

BMI of ____ to ____ Normal Weight

A

18.5-24.9

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10
Q

With a Leptin excess, what happens to insulin levels?

A

Hypoinsulinemia

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11
Q

What is unique about Ghrelin’s regulation?

A

GOAT alters fatty acids to alter Ghrelin functionality

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12
Q

Leptin _____ POMC activity and _____ NPY activity to ultimately promote ______ and ______

A
  • Promotes
  • Inhibits
  • Satiety and Energy Burning
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13
Q

With a leptin deficiency, what happens to insulin levels?

A

Hyperinsulinemia

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14
Q

In response to distension or chemi changes, Vagal Afferents send messages to ______ to connect with the hypothalamus

A

Nucleus Tract Soliatrius (NTS)

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15
Q

BMI of ____ is clinically obese

A

30

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16
Q

Endocanniboids are fatty acids made in the ____-synaptic space to ultimately inhibit NT release and promote appetite.

A

POST

17
Q

Ghrelin promotes appetite by promoting which Arcuate neuronal group?

A

NPY/AgRP

18
Q

Ghrelin is made in the stomach and Duod; what are its 3 main actions?

A
  1. boost GH
  2. Stim appetite
  3. Gain weight