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Oral Biology 1 > Tooth Development > Flashcards

Tooth Development Flashcards

1
Q

What are the primary embryonic layers

A

Ectoderm
Mesoderm
Endoderm

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2
Q

What is tooth enamel derived from

A

Ectoderm

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3
Q

What are all tooth structures besides the enamel derived from

A

Ectomesenchyme

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4
Q

What is the ectomesenchyme

A

Part of the neural crest that develops beside the primitive nervous system (ectoderm)

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5
Q

What do teeth develop from

A

Tooth germs

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6
Q

What is another name for the neural crest

A

Ectomesenchyme

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7
Q

What is developed in the initiation stage

A

Dental lamina

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8
Q

What are the different stages of tooth development

A 
Initiation
Morphogenetic
Cytodifferentiation
Matrix secretion
Root formation
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9
Q

Name in order of first to last, the parts of tooth that are developed

A 
Dental lamina
Bud
Cap
Bell
Erupting tooth
Bone
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10
Q

When does the primary epithelial band develop

A

Approximately 6 weeks

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11
Q

What does the primary epithelial band appear as

A

Thickening of epithelium of embryonic mouth (stomodaeum)

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12
Q

When does the dental lamina develop

A

Approximately 7 weeks

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13
Q

What does the primary epithelial band divide into

A

Vestibular lamina and dental lamina

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14
Q

What does the vestibular lamina form

A

Buccal sulcus

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15
Q

What does the dental lamina form

A

Enamel organ

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16
Q

What develops at the morphogenesis stage

A

Bud and cap

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17
Q

When does the enamel bud develop

A

8-10 weeks

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18
Q

What happens during the bud stage

A

Dental lamina thickens into an enamel bud and the dental papilla appears

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19
Q

When does the enamel cap develop

A

11 weeks

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20
Q

What happens during the cap stage

A

Enamel organ forms a cap over the papilla and the external enamel epithelium and internal enamel epithelium meet at the cervical loop

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21
Q

What develops during cytodifferentiation

A

The bell

22
Q

When does the bell develop

A

14 weeks

23
Q

What happens during the bell stage

A

There are more cell layers differentiated and tooth shape is being defined

24
Q

What are the layers of the enamel organ at the bell stage

A

Internal enamel epithelium
Stratum intermedium
External enamel epithelium
Stellate reticulum

25
Q

What happens at 12 weeks

A

An extension appears on the lingual side of the dental lamina - this is the dental lamina of the permanent tooth

26
Q

What develops during matrix secretion

A

The eruption of the tooth

27
Q

When does the late bell stage take place

A

18 weeks

28
Q

What does the late bell stage look like

A

Crown shape is well defined, apposition of enamel and dentine begins

29
Q

What develops into odontoblasts

A

Dental papilla cells adjacent to the internal enamel epithelium

30
Q

What do odontoblasts do

A

Lay down a dentine matrix

31
Q

What forms enamel

A

Ameloblasts

32
Q

What happens during dentinogenesis

A

Odontoblast differentiation from internal enamel epithelium
Deposition of dentine matrix
Mineralisation of dentine

33
Q

What is unmineralised dentine called

A

Predentine

34
Q

How is enamel formed

A

The protein matrix is deposited and then the organic part is removed and mineralisation is completed - maturation

35
Q

What happens during ameloblast differentiation

A

Dentine induces IEE cells to differentiate into ameloblasts which elongate becoming columnar and the nucleus migrates to the basal end of the cell

36
Q

What happens during the secretory phase of amelogenesis

A

Ameloblasts become secretory cells which synthesise and secrete the enamel matrix proteins
The matrix is then partially mineralised

37
Q

What happens during the maturation phase of amelogenesis

A

Most of the matrix proteins are removed, mineral content of enamel is increased
Mature enamel is 95% mineral

38
Q

What happens during the protection phase of amelogenesis

A

Ameloblasts regress to form a protective layer - the reduced enamel epithelium
Eruption takes place and epithelial attachment forms

39
Q

What is root shape defined by

A

The apical growth of the cervical loop

40
Q

When in root formation, what is the cervical loop called

A

Hertwig’s epithelial root sheath

41
Q

What is Hertwig’s epithelial root sheath

A

2-cell-layered structure

42
Q

What does HERS induce

A

Formation of root dentine

43
Q

What happens once the initial layer of root dentine is formed

A

HERS breaks up

44
Q

What do the remnants of HERS appear as once they are broken up

A

Debris of malassez we high may develop into a cyst

45
Q

What differentiates into cementoblasts

A

Mesenchymal cells from the follicle

46
Q

What do cementoblasts form

A

Cementum

47
Q

What are Sharpey’s fibres

A

Fibres from the developing PDL

48
Q

Name the type of tissue, origin and products of the enamel organ

A

Epithelium
Ectoderm
Enamel

49
Q

Name the type of tissue, origin and products of the dental papilla

A

Ectomesenchyme
Neural crest
Dentine and pulp

50
Q

Name the type of tissue, origin and products of the dental follicle

A

Ectomesenchyme
Neural crest
Cementum, PDL and part of the alveolar bone

51
Q

What is hypodontia

A

Having less teeth than you are supposed to have

52
Q

What is supernumerary

A

An extra tooth

Oral Biology 1 (11 decks)

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