Uworld 1 Flashcards

1
Q

Pineal gland tumor features

A
limited upward gaze
upper eyelad retraction
pupillary abnormalities
papilledema
HA
Vomiting
Ataxia
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2
Q

Transposition of great vessels x-ray and cardio findings

A

single s2
+- vsd
narrow mediastinum

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3
Q

Tetrology of fallot findings

A

harsh pulmonic stenosis murmur(systolic)
VSD
Boot shaped heart
Big RV

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4
Q

Tricuspid atresia findings

A

single s2
VSD
minimal pull flow

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5
Q

Truncus arteriosus findings

A

single s2 systolic ejection murmur

increased pulmonary blood flow and edema

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6
Q

cysteine stone

A

radiolucent, peds/teen,hexagon crystal,+nitropruside test

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7
Q

CHARGE syndrome

A
Colboma(hole in the eye-word pupil
Heart (TOF/VSD)
Atresia
Retardation
Genitourinary abnormalities
Ear-shape and function
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8
Q
Beckwith /wiedman Syndrome 
Path
Exam
Complications
Surveillance
A

Deregulation of imprinted gene expression in chrome 11p15
exam: macrosomia, rapid growth, omphalacle or jumbo hernia, macroglossia, hemihyperplasia
Complications: wilms tumor, hepatoblastoma
Surveillance:AFP, Abdominal ultrasound

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9
Q

what markers are elevated in choriocarcinoma

A

CA19-9, CEA

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10
Q

Chromium Def sx

A

impaired glucose control

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11
Q

Copper deficiency sx

A
Brittle Hair
Skin depigmentation
Anemia
ataxia
peripheral neuropathy
Osteoporosis
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12
Q

selenium deficiency sx

A

Thyroid dysfunction
cardiomyopathy
immune dysfunction

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13
Q

zinc deficiency sx

A
Alopecia
Pustular skin rash 
Hypogonadism
Impaired wound healing
immune dysfunction
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14
Q

Methotrexate MOA and Adverse Events

A

Folate inhibition’s

  • hepatotoxicty
  • stomatitis
  • cytopenias
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15
Q

Hydroxychloroquine MOA

SE

A

TNF & IL1 supressor

-retinopathy

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16
Q

Sulfasalzine MOA, SE

A

TNF, IL-1 supressor

-hepatotoxicty
stomatitis
Hemolytic anemia

17
Q

TNF alpha inhibitors SE

A

infection
demyelination
congestive 💜 failure
malignancy

18
Q

Diverticulitis + urine findings

A

LLQ pain
nausea and vomiting
+Leuk, - nitrate

19
Q

Rocky Mountain Spotted fever labs

A

⬇️ platelets,⬇️ Na,⬆️ ast/alt

20
Q

Rocky Mountain Spotted fever tx

A

doxy

21
Q

Risk factors for placenta previa

A

previous c section
prior previa
multiple gestations
prior uterine surgery

22
Q

infertility tx PCOS after weight loss

A

Letrozole-aromatase inhibitor

23
Q

what increases t4 binding globulin

A

estrogen

24
Q

electrolyte abnormality multiple myeloma

A

Hyper Ca

25
Q

Granulose cell. tumor marks

A

Estradiol/inhibin

26
Q

HUS triad

A

Hemolytic anemia
Thrombocytopenia
Acute kidney injury

27
Q

what causes HELLP

A

Distention of liver capsule

28
Q

2nd most important lifestyle change HTN

A

DASH diet

29
Q

Paroxsymal noctural hemoglobinuria

A
Hemolysis
fatigue
increased risk for venous thrombosis
no CD55 or 59
Tx=iron and folate, eculizumab
30
Q

Sarcoid neuro sx

A

Facial nerve palsy
Central DI
Hypogonadotropic Hypogonadism
⬆️ Ca2+