Hematology

Question 1

What is the most common inherited bleeding disorder?

Answer 1

Von Wilebrand Disease

Question 2

What is Prothrombin time? (PT)

Answer 2

measures the time it takes blood to clot when exposed to tissue factor, which is a test of the extrinsic coagulation pathway

Question 3

What inheritance pattern is von Wildebrand Disease?

Answer 3

autosomal dominant

Question 4

a 30-year-old woman with a recurrent history of nosebleeds and heavy menses. She recently read that taking a baby aspirin was good for the heart. However, ever since she started taking aspirin, she has been experiencing more and more nosebleeds. Her father and paternal uncle similarly have histories of prolonged nosebleeds. Labs show increased PTT, normal PT, and increased bleeding time.

What dz?

Answer 4

vWD

Question 5

What labs should you run in someone you suspect has vWB?

Answer 5

Normal platelets, PT and PTT

Decreased von Willebrand’s factor (vWF)

Question 6

What is the treatment for Von Willebrand Disease?

Answer 6

DDAVP (Desmopressin)